Biphenyl

Biphenyl

SCHEMBL909901

C1CCC(C2CCCCC2)CC1.O=C(O)OC(=O)O.OO

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.44
CES2 O00748 1/20 0.39
CES1 P23141 1/20 0.39
HSD11B1 P28845 1/20 0.38
GRM2 Q14416 1/20 0.35
EPHX1 P07099 7/20 0.35
NPC1 O15118 3/20 0.35
RAB9A P51151 2/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
MAPT P10636 1/20 0.35
KDM4E B2RXH2 1/20 0.35
CYP3A4 P08684 1/20 0.35
EPHX2 P34913 1/20 0.35
HDAC8 Q9BY41 1/20 0.33
HDAC6 Q9UBN7 1/20 0.33
LMNA P02545 1/20 0.33
SLC18A3 Q16572 1/20 0.32
TSHR P16473 1/20 0.32
HPGD P15428 1/20 0.32
HTT P42858 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL1537198 0.83 ALDH1A1 (0.44) ALDH1A1CES2CES1HSD11B1GRM2
Biphenyl SCHEMBL6450557 0.83 ALDH1A1 (0.44) ALDH1A1CES2CES1HSD11B1GRM2
Bicarbonate SCHEMBL7025736 0.82 ALDH1A1 (0.57) ALDH1A1CES2CES1HSD11B1GRM2
Bicarbonate SCHEMBL10775900 0.82 ALDH1A1 (0.57) ALDH1A1CES2CES1HSD11B1GRM2
Bicarbonate SCHEMBL10581815 0.82 ALDH1A1 (0.57) ALDH1A1CES2CES1HSD11B1GRM2
Biphenyl SCHEMBL2169497 0.82 ALDH1A1 (0.57) ALDH1A1CES2CES1HSD11B1GRM2
Cyclopropane SCHEMBL4440814 0.82 FFAR3 (0.38) CES2CES1
Cyclopentane SCHEMBL7058888 0.82 FFAR3 (0.38) CES2CES1
Cyclohexane SCHEMBL9535898 0.82 FFAR3 (0.38) CES2CES1
Cyclopropane SCHEMBL11399095 0.82 FFAR3 (0.38) CES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109762117-A The synthetic method of polyether polyol 山东蓝星东大有限公司 2019-05-17 CN claimed
CN-108634477-A A kind of manufacturing method of internal height-increasing shoe 广州市鸿峥实业有限公司 2018-10-12 CN claimed
EP-3652245-B1 ADDITIVE MIXTURES FOR PLASTICS, LASER-MARKABLE POLYMER COMPOSITIONS CONTAINING SAME, AND USE THEREOF CLARIANT INT LTD (CH) 2024-04-24 EP disclosed
US-11945913-B2 Thermosetting polyimide resin and manufacturing method thereof, composition, prepolymer, film, adhesive, and use thereof CHIN YEE CHEMICAL INDUSTRIES CO., LTD. (TW) 2024-04-02 US disclosed
EP-3652241-B1 ADDITIVE MIXTURES FOR PLASTICS, LASER-MARKABLE POLYMER COMPOSITIONS CONTAINING SAME AND USE THEREOF CLARIANT INT LTD (CH) 2023-04-19 EP disclosed
CN-115894804-A Copolymer containing PVDF unit, preparation method thereof, humidity-sensitive film and application of humidity-sensitive film 广州奥松电子股份有限公司 2023-04-04 CN disclosed
CN-115286767-A Antibacterial fluorine modified epoxy vinyl ester resin, preparation method thereof and multi-mechanism synergetic universal anticorrosive coating 海洋化工研究院有限公司 2022-11-04 CN disclosed
WO-2020186482-A1 POLYMER AND PREPARATION METHOD AND APPLICATION THEREOF 深圳大学 2020-09-24 WO disclosed
CN-107556433-B Dynamic polymer elastomer with hybrid cross-linked network and application thereof 翁秋梅 2020-07-31 CN disclosed
EP-3679095-A1 SYNERGISTIC FLAME RETARDANT COMBINATIONS FOR POLYMER COMPOSITIONS AND USE THEREOF Clariant Plastics & Coatings Ltd (CH) 2020-07-15 EP disclosed
EP-3679093-A1 FLAME RETARDANT COMBINATIONS FOR POLYMER COMPOSITIONS AND USE THEREOF Clariant Plastics & Coatings Ltd (CH) 2020-07-15 EP disclosed
US-20110251310-A1 Hydrophosphorylation of Phosphonous Acid Derivatives for Flame Retardants CLARIANT FINANCE (BVI) LIMITED (VG) 2011-10-13 US disclosed
EP-2343344-A1 Encapsulation of pigments with polymer latex prepared by mini-emulsion polymerization Akzo Nobel Coatings International B.V. (NL) 2011-07-13 EP disclosed
US-20110098372-A1 FOAMABLE POLYAMIDES BASF SE (DE) 2011-04-28 US disclosed
WO-2011032905-A1 ENCAPSULATION OF PIGMENTS WITH POLYMER LATEX PREPARED BY MINI-EMULSION POLYMERIZATION AKZO NOBEL COATINGS INTERNATIONAL B.V. (NL) 2011-03-24 WO disclosed
US-20110015285-A1 FOAMABLE COPOLYMERS BASED ON RENEWABLE RAW MATERIALS BASF SE (DE) 2011-01-20 US disclosed
US-20080194715-A1 Use of Copolymers Comprising Polyisobutene in Cosmetic Compositions BASF AKTIENGESELLSCHAFT (DE) 2008-08-14 US disclosed
US-20070148460-A1 Pigments sheathed with polyaddition products, method for their produciton and use thereof BASF AKTIENGESELLSCHAFT (DE) 2007-06-28 US disclosed
US-20060173149-A1 Method for producing polymers having isotactic or syndiotactic regions BASF AKTIENGESELLSCHAFT (DE) 2006-08-03 US disclosed
US-20060074002-A1 Partially esterified copolymers of monoethylenically unsaturated dicarboxylic anthydrides, vinylaromatic compounds and other monoethylenically unsaturated monomers containing heteroatoms BASF AKTIENGESELLSCHAFT (DE) 2006-04-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110251310-A1 Hydrophosphorylation of Phosphonous Acid Derivatives for Flame Retardants NR1H3, NR1H2, NR1H4 ALDH1A1 3256/4885CES2 1145/4885CES1 710/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.