Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CB | P42338 | 4/20 | 0.83 |
| ▸ | PIK3CA | P42336 | 18/20 | 0.77 |
| ▸ | PIK3CD | O00329 | 4/20 | 0.77 |
| ▸ | PIK3R1 | P27986 | 4/20 | 0.77 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL909478 | 0.91 | PIK3CA (0.81) | PIK3CBPIK3CAPIK3CDPIK3R1PIK3CG | |
| SCHEMBL6523363 | 0.89 | PIK3CB (0.76) | PIK3CBPIK3CAPIK3CDPIK3R1PIK3CG | |
| SCHEMBL6517150 | 0.89 | PIK3CB (0.76) | PIK3CBPIK3CAPIK3CDPIK3R1PIK3CG | |
| SCHEMBL908303 | 0.87 | PIK3CB (0.61) | PIK3CBPIK3CAPIK3CDPIK3R1PIK3CG | |
| SCHEMBL910025 | 0.87 | PIK3CB (0.91) | PIK3CBPIK3CAPIK3CDPIK3R1PIK3CG | |
| SCHEMBL6518609 | 0.87 | PIK3CB (0.91) | PIK3CBPIK3CAPIK3CDPIK3R1PIK3CG | |
| SCHEMBL3568141 | 0.86 | PIK3CB (1.00) | PIK3CBPIK3CAPIK3CDPIK3R1PIK3CG | |
| SCHEMBL4523893 | 0.86 | PIK3CB (0.77) | PIK3CBPIK3CAPIK3CDPIK3R1PIK3CG | |
| SCHEMBL4526879 | 0.85 | PIK3CB (0.76) | PIK3CBPIK3CAPIK3CDPIK3R1PIK3CG | |
| SCHEMBL31156977 | 0.84 | PIK3CA (0.77) | PIK3CBPIK3CAPIK3CDPIK3R1PIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2276750-A2 | SUBSTITUTED PYRIMIDINES AND TRIAZINES AND THEIR USE IN CANCER THERAPY | Auckland Uniservices Limited (NZ) | 2011-01-26 | — | — | EP | disclosed |
| WO-2009120094-A2 | SUBSTITUTED PYRIMIDINES AND TRIAZINES AND THEIR USE IN CANCER THERAPY | AUCKLAND UNISERVICES LIMITED (NZ) | 2009-10-01 | — | — | WO | disclosed |