Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.53 |
| ▸ | RECQL | P46063 | 2/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.53 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | AKT1 | P31749 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10933652 | 0.86 | KMT2A (0.46) | NFE2L2KMT2AMEN1HDAC1HDAC2 | |
| SCHEMBL27490875 | 0.86 | KMT2A (0.46) | NFE2L2KMT2AMEN1HDAC1HDAC2 | |
| SCHEMBL27714274 | 0.84 | KMT2A (0.44) | NFE2L2KMT2AMEN1HDAC1HDAC2 | |
| SCHEMBL17553130 | 0.83 | TSHR (0.47) | KMT2AMEN1RECQLALDH1A1MAPK1 | |
| SCHEMBL9869968 | 0.80 | CYP1A2 (0.64) | NFE2L2KMT2AMEN1HDAC1HDAC2 | |
| SCHEMBL15868826 | 0.80 | CYP1A2 (0.64) | NFE2L2KMT2AMEN1HDAC1HDAC2 | |
| SCHEMBL9869964 | 0.80 | CYP1A2 (0.64) | NFE2L2KMT2AMEN1HDAC1HDAC2 | |
| SCHEMBL11015842 | 0.78 | CYP1A2 (0.71) | KMT2AMEN1HDAC1HDAC2HDAC3 | |
| SCHEMBL9587360 | 0.77 | MAPT (0.49) | KMT2AMEN1ALDH1A1MAPTNPC1 | |
| SCHEMBL20414337 | 0.76 | ALDH1A1 (0.50) | KMT2AMEN1RECQLALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0245505-B2 | TERMINAL-MODIFIED BLOCK COPOLYMER AND COMPOSITION CONTAINING SAID COPOLYMER | ASAHI CHEMICAL IND (JP) | 1996-08-14 | — | — | EP | disclosed |