Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.36 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9235403 | 0.87 | TDP1 (0.50) | TDP1ALDH1A1GLACHRM2CHRM4 | |
| SCHEMBL16492331 | 0.76 | TDP1 (0.53) | TDP1ALDH1A1GLACHRM2CHRM4 | |
| SCHEMBL1813515 | 0.76 | TDP1 (0.46) | TDP1ALDH1A1GLACHRM2CHRM4 | |
| SCHEMBL17275005 | 0.75 | TDP1 (0.45) | TDP1ALDH1A1GLACHRM2CHRM4 | |
| SCHEMBL16709774 | 0.75 | CHRM2 (0.44) | TDP1ALDH1A1GLACHRM2CHRM4 | |
| SCHEMBL14763764 | 0.74 | FFAR1 (0.41) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL5704259 | 0.73 | TDP1 (0.50) | TDP1ALDH1A1GLACHRM2CHRM4 | |
| SCHEMBL15667106 | 0.73 | TDP1 (0.50) | TDP1ALDH1A1GLACHRM2CHRM4 | |
| SCHEMBL730116 | 0.73 | TDP1 (0.46) | TDP1ALDH1A1GLACHRM2CHRM4 | |
| SCHEMBL17275007 | 0.73 | TDP1 (0.46) | TDP1ALDH1A1GLACHRM2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0576617-B1 | COMPOSITION AND METHOD CONTAINING OPTICALLY PURE (S) METOPROLOL | SEPRACOR INC (US) | 1996-08-07 | — | — | EP | disclosed |
| EP-0677291-A2 | Composition and method containing optically pure (S) metoprolol | SEPRACOR, INC. (US) | 1995-10-18 | — | — | EP | disclosed |
| EP-0576617-A1 | COMPOSITION AND METHOD CONTAINING OPTICALLY PURE (S) METOPROLOL. | SEPRACOR INC (US) | 1994-01-05 | — | — | EP | disclosed |
| WO-1992016197-A1 | COMPOSITION AND METHOD CONTAINING OPTICALLY PURE (S) METOPROLOL | SEPRACOR INC. (US) | 1992-10-01 | — | — | WO | disclosed |