SCHEMBL730116

SCHEMBL730116

c1ccc(C(COCC2CO2)OCC2CO2)cc1

nearest known ligand 0.46

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.46
ALDH1A1 P00352 3/20 0.39
GLA P06280 1/20 0.39
TSHR P16473 2/20 0.38
TP53 P04637 1/20 0.38
CYP3A4 P08684 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
HIF1A Q16665 1/20 0.38
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
CHRM2 P08172 2/20 0.35
CHRM4 P08173 2/20 0.35
CHRM5 P08912 2/20 0.35
CHRM1 P11229 2/20 0.35
CHRM3 P20309 2/20 0.35
MGLL Q99685 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10431334 0.87 TDP1 (0.41) TDP1ALDH1A1GLATSHRTP53
SCHEMBL15666864 0.84 TDP1 (0.44) TDP1ALDH1A1GLATSHRTP53
SCHEMBL29717315 0.83 TDP1 (0.50) TDP1ALDH1A1GLATSHRTP53
SCHEMBL15689423 0.82 TDP1 (0.47) TDP1ALDH1A1GLATSHRTP53
SCHEMBL20504407 0.82 TDP1 (0.47) TDP1ALDH1A1GLATSHRTP53
SCHEMBL5162429 0.82 TDP1 (0.47) TDP1ALDH1A1GLATSHRTP53
SCHEMBL29706148 0.82 ALDH1A1 (0.59) TDP1ALDH1A1GLATSHRTP53
SCHEMBL15667106 0.81 TDP1 (0.50) TDP1ALDH1A1GLATSHRTP53
SCHEMBL29086782 0.80 ALDH1A1 (0.46) TDP1ALDH1A1GLATSHRTP53
SCHEMBL8068723 0.79 TDP1 (0.45) TDP1ALDH1A1GLATSHRTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200317953-A1 POLYETHERS CONTAINING NON-BISPHENOLIC CYCLIC GROUPS SWIMC LLC (US) 2020-10-08 US claimed
EP-2788398-B1 SULFIDE EXTENDED EPOXY RESINS AND BARRIER COATINGS APPLICATIONS THEREOF SUN CHEMICAL CORP (US) 2018-07-25 EP claimed
US-9624380-B2 Sulfide extended epoxy resins and barrier coating applications thereof SUN CHEMICAL CORPORATION (US) 2017-04-18 US claimed
EP-3146009-A1 POLYETHERS CONTAINING NON-BISPHENOLIC CYCLIC GROUPS Valspar Sourcing, Inc. (US) 2017-03-29 EP claimed
US-20170051177-A1 POLYETHERS CONTAINING NON-BISPHENOLIC CYCLIC GROUPS SWIMC LLC 2017-02-23 US claimed
WO-2015179064-A1 POLYETHERS CONTAINING NON-BISPHENOLIC CYCLIC GROUPS VALSPAR SOURCING, INC. (US) 2015-11-26 WO claimed
US-20140370220-A1 OVERPRINT VARNISHES WITH NON-AQUOUS DISPERSIONS SUN CHEMICAL CORPORATION (US) 2014-12-18 US claimed
US-20140342091-A1 SULFIDE EXTENDED EPOXY RESINS AND BARRIER COATING APPLICATIONS THEREOF SUN CHEMICAL CORPORATION (US) 2014-11-20 US claimed
EP-2788398-A2 SULFIDE EXTENDED EPOXY RESINS AND BARRIER COATINGS APPLICATIONS THEREOF Sun Chemical Corporation (US) 2014-10-15 EP claimed
WO-2013090702-A2 SULFIDE EXTENDED EPOXY RESINS AND BARRIER COATINGS APPLICATIONS THEREOF SUN CHEMICAL CORPORATION (US) 2013-06-20 WO claimed
CN-114525072-A Polyethers containing cyclic groups other than bisphenols 宣伟投资管理有限公司 2022-05-24 CN disclosed
US-20200317953-A1 POLYETHERS CONTAINING NON-BISPHENOLIC CYCLIC GROUPS SWIMC LLC (US) 2020-10-08 US disclosed
US-10793742-B2 Polyethers containing non-bisphenolic cyclic groups VALSPAR SOURCING, INC. (US) 2020-10-06 US disclosed
EP-2788398-B1 SULFIDE EXTENDED EPOXY RESINS AND BARRIER COATINGS APPLICATIONS THEREOF SUN CHEMICAL CORP (US) 2018-07-25 EP disclosed
CN-104039862-B Sulfide-extended epoxy resin and application of barrier coating thereof 太阳化学公司 2017-12-22 CN disclosed
WO-2009132010-A1 METHODS AND SYSTEMS FOR MAKING THIOL COMPOUNDS FROM TERMINAL OLEFINIC COMPOUNDS CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2009-10-29 WO disclosed
US-20090264669-A1 Methods and Systems for Making Thiol Compounds from Terminal Olefinic Compounds CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2009-10-22 US disclosed
EP-1940992-A1 MERCAPTAN-HARDENED EPOXY POLYMER COMPOSITIONS AND PROCESSES FOR MAKING AND USING SAME Chevron Phillips Chemical Company LP (US) 2008-07-09 EP disclosed
US-20070112100-A1 MERCAPTAN-HARDENED EPOXY POLYMER COMPOSITIONS AND PROCESSES FOR MAKING AND USING SAME CHEVRON PHILLIPS CHEMICAL COMPANY, LP 2007-05-17 US disclosed
WO-2007022217-A1 MERCAPTAN-HARDENED EPOXY POLYMER COMPOSITIONS AND PROCESSES FOR MAKING AND USING SAME CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2007-02-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090264669-A1 Methods and Systems for Making Thiol Compounds from Terminal Olefinic Compounds TST, HHAT, GSTO1 TDP1 2381/4885ALDH1A1 157/4885GLA 2787/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.