SCHEMBL909939

SCHEMBL909939

COC(=O)C(=O)C1CCCCC1

nearest known ligand 0.59

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.59
CES1 P23141 1/20 0.59
HDAC8 Q9BY41 1/20 0.44
HDAC6 Q9UBN7 1/20 0.44
SMN1; SMN2 Q16637 3/20 0.44
NPSR1 Q6W5P4 1/20 0.39
TSHR P16473 2/20 0.38
ALDH1A1 P00352 1/20 0.38
EPHX1 P07099 2/20 0.38
RECQL P46063 1/20 0.38
POLB P06746 1/20 0.37
MAPK1 P28482 1/20 0.37
HSD17B10 Q99714 1/20 0.36
NAAA Q02083 1/20 0.36
EPHX2 P34913 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7640853 1.00 CES2 (0.59) CES2CES1HDAC8HDAC6SMN1; SMN2
SCHEMBL7634052 1.00 CES2 (0.59) CES2CES1HDAC8HDAC6SMN1; SMN2
SCHEMBL5393755 0.98 CES2 (0.55) CES2CES1HDAC8HDAC6SMN1; SMN2
SCHEMBL874374 0.93 CES2 (0.48) CES2CES1HDAC8HDAC6SMN1; SMN2
SCHEMBL7644723 0.87
SCHEMBL10009844 0.81 CES2 (0.46) CES2CES1HDAC8HDAC6SMN1; SMN2
SCHEMBL10009607 0.81 CES2 (0.46) CES2CES1HDAC8HDAC6SMN1; SMN2
SCHEMBL10009837 0.81 CES2 (0.46) CES2CES1HDAC8HDAC6SMN1; SMN2
SCHEMBL10009603 0.81 CES2 (0.46) CES2CES1HDAC8HDAC6SMN1; SMN2
SCHEMBL18473773 0.80 CES2 (0.46) CES2CES1HDAC8HDAC6SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120004771-A Method for producing organic sulfinate compound 中国石油化工股份有限公司 2025-05-16 CN claimed
US-9487602-B2 Furan based resin, process for the preparation thereof, and use of the compound DSM IP ASSETS B.V. (NL) 2016-11-08 US claimed
US-20130109822-A1 FURAN BASED RESIN, PROCESS FOR THE PREPARATION THEREOF, AND USE OF THE COMPOUND DSM IP ASSETS B.V. (NL) 2013-05-02 US claimed
US-20110306735-A1 PROCESS FOR THE PREPARATION OF A HYDROXY-AROMATIC RESIN; HYDROXY-AROMATIC RESIN, AND MODIFICATION THEREOF DSM IP ASSETS B.V. (NL) 2011-12-15 US claimed
US-20110021740-A1 FURAN BASED RESIN, PROCESS FOR THE PREPARATION THEREOF, AND USE OF THE COMPOUND DSM IP ASSETS B.V. (NL) 2011-01-27 US claimed
EP-2222656-A1 FURAN BASED RESIN, PROCESS FOR THE PREPARATION THEREOF, AND USE OF THE COMPOUND DSM IP Assets B.V. (NL) 2010-09-01 EP claimed
US-20090203851-A1 Process for the Preparation of a Hydroxy-Aromatic Resin: Hydroxy-Aromatic Resin, and Modification Thereof DSM IP ASSETS B.V. (NL) 2009-08-13 US claimed
WO-2009077587-A1 FURAN BASED RESIN, PROCESS FOR THE PREPARATION THEREOF, AND USE OF THE COMPOUND DSM IP ASSETS B.V. (NL) 2009-06-25 WO claimed
EP-2024317-A2 PROCESS FOR THE PREPARATION OF A HYDROXY-AROMATIC RESIN; HYDROXY-AROMATIC RESIN, AND MODIFICATION THEREOF DSMIP Assets B.V. (NL) 2009-02-18 EP claimed
WO-2007140941-A2 PROCESS FOR THE PREPARATION OF A HYDROXY-AROMATIC RESIN; HYDROXY-AROMATIC RESIN, AND MODIFICATION THEREOF DSM IP ASSETS B.V. (NL) 2007-12-13 WO claimed
CN-1434815-A Method for the production of 2-coumarone and substituted 2-coumarones DSM FINE CHEM AUSTRIA GMBH (AT) 2003-08-06 CN claimed
CN-120004771-A Method for producing organic sulfinate compound 中国石油化工股份有限公司 2025-05-16 CN disclosed
CN-115175658-A Perfume system for perfumed consumer products 弗门尼舍有限公司 2022-10-11 CN disclosed
CN-108738320-A 4- amino -2- (1H- pyrazolos [3 as the cGMP conditioning agents for treating angiocardiopathy, 4-b] pyridin-3-yl) -6- oxos -6,7- dihydro -5H- pyrrolo-es [2,3-d] pyrimidine derivatives and respective (1H- indazole -3- bases) derivative 默沙东公司 2018-11-02 CN disclosed
US-9487602-B2 Furan based resin, process for the preparation thereof, and use of the compound DSM IP ASSETS B.V. (NL) 2016-11-08 US disclosed
CN-1434815-A Method for the production of 2-coumarone and substituted 2-coumarones DSM FINE CHEM AUSTRIA GMBH (AT) 2003-08-06 CN disclosed
US-6348617-B1 REACTING PYRUVIC ACID COMPOUND IN WATER WITH AMMONIUM OR ALKALI METAL BISULFITE TO GIVE AQUEOUS SOLUTION OF BISULFITE ADDUCT, ISOLATING BY PHASE SEPARATION, OPTIONALLY USING HYDROPHOBIC SOLVENT, CONTACTING WITH ACID TO DECOMPOSE ADDUCT SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-02-19 US disclosed
WO-2000053313-A2 LANTHANIDE CATALYSTS FOR SYNTHESIS OF COMPOUNDS AND COMBINATORIAL LIBRARIES ARQULE, INC. (US) 2000-09-14 WO disclosed
EP-0937703-A1 METHOD FOR PURIFYING PYRUVIC ACID COMPOUNDS SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1999-08-25 EP disclosed
EP-0003301-A1 N-Sulfenyl-carbamoyl-oximes, preparation thereof and use thereof as insecticides, acaricides, nematocides BAYER AG (DE) 1979-08-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090203851-A1 Process for the Preparation of a Hydroxy-Aromatic Resin: Hydroxy-Aromatic Resin, and Modification Thereof HRH3, HRH1, C9 CES2 973/4885CES1 2109/4885HDAC8 3184/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.