Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAOX | Q6QHF9 | 7/20 | 0.70 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | THRB | P10828 | 2/20 | 0.44 |
| ▸ | BLM | P54132 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.44 |
| ▸ | GABRP | O00591 | 1/20 | 0.44 |
| ▸ | GABRD | O14764 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.44 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.44 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.44 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.44 |
| ▸ | GABRR2 | P28476 | 1/20 | 0.44 |
| ▸ | SLC6A1 | P30531 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9103695 | 0.93 | PAOX (0.65) | PAOXLMNATHRBBLMKMT2A | |
| SCHEMBL219402 | 0.87 | — | — | |
| SCHEMBL433840 | 0.85 | — | — | |
| Hydrochloric Acid SCHEMBL1128658 | 0.85 | — | — | |
| SCHEMBL23872982 | 0.82 | PAOX (1.00) | PAOXLMNATHRBBLMKMT2A | |
| SCHEMBL806164 | 0.82 | — | — | |
| SCHEMBL16297742 | 0.82 | PAOX (1.00) | PAOXLMNATHRBBLMKMT2A | |
| Hydrochloric Acid SCHEMBL11569445 | 0.82 | — | — | |
| SCHEMBL9623780 | 0.82 | PAOX (1.00) | PAOXLMNATHRBBLMKMT2A | |
| SCHEMBL18533504 | 0.82 | PAOX (1.00) | PAOXLMNATHRBBLMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5547982-A | CONTAIN AT LEAST ONE FUNCTIONAL KETONE OR ALDEHYDE GROUP, OPTIONALLY CONJUGATED AS A LINKABLE HYDRAZONE COMPLEX | JOHNSON MATTHEY, INC. (US) | 1996-08-20 | — | — | US | disclosed |