SCHEMBL909947

SCHEMBL909947

COc1ccc(CCC=O)cc1O

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.63
CYP3A4 P08684 1/20 0.63
TSHR P16473 1/20 0.63
NFKB1 P19838 1/20 0.63
MEN1 O00255 1/20 0.61
LMNA P02545 1/20 0.61
APEX1 P27695 1/20 0.61
KMT2A Q03164 1/20 0.61
TUBB4A P04350 3/20 0.59
TUBB P07437 3/20 0.59
TUBA3C P0DPH7 3/20 0.59
TUBA1B P68363 3/20 0.59
TUBA4A P68366 3/20 0.59
TUBB4B P68371 3/20 0.59
TUBB3 Q13509 3/20 0.59
TUBB2A Q13885 3/20 0.59
TUBB8 Q3ZCM7 3/20 0.59
TUBA3E Q6PEY2 3/20 0.59
TUBA1A Q71U36 3/20 0.59
TUBA1C Q9BQE3 3/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30690114 1.00 CYP1A2 (0.63) CYP1A2CYP3A4TSHRNFKB1MEN1
SCHEMBL910431 0.87 TAAR1 (0.65) CYP1A2CYP3A4TSHRNFKB1LMNA
SCHEMBL3390749 0.84 GAA (0.62) CYP1A2CYP3A4TSHRNFKB1MEN1
SCHEMBL910624 0.84 ATM (0.59) CYP1A2CYP3A4CYP19A1ALDH1A1
SCHEMBL31490018 0.84 ATM (0.59) CYP1A2CYP3A4CYP19A1ALDH1A1
SCHEMBL28376731 0.83 CYP3A4 (0.63) CYP1A2CYP3A4TSHRNFKB1MEN1
SCHEMBL1936524 0.83 CYP1A2 (0.58) CYP1A2CYP3A4TSHRNFKB1MEN1
SCHEMBL28634023 0.81 AKR1B1 (0.54) CYP1A2CYP3A4TSHRNFKB1MEN1
SCHEMBL584542 0.81 KDM4E (0.47) CYP1A2CYP3A4TSHRNFKB1MEN1
SCHEMBL19043113 0.80 KMT2A (0.49) CYP1A2CYP3A4MEN1KMT2AGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117820101-A Amplified preparation method of Edwan sweet 上海再启生物技术有限公司 2024-04-05 CN claimed
CN-117586341-A Method for synthesizing Aide wan sweet 南通市常海食品添加剂有限公司 2024-02-23 CN claimed
CN-113620792-A Preparation method of 3-hydroxy-4-methoxy phenylpropylaldehyde 绵阳三香汇生物科技有限公司 2021-11-09 CN claimed
CN-110818774-A Synthetic method of 40000 times dipeptide high-power sweetener 暨南大学 2020-02-21 CN claimed
CN-109535225-A A kind of compound and its synthetic method and application 暨南大学 2019-03-29 CN claimed
CN-109232711-A A method of synthesis Advantest sweet tea 厦门大学 2019-01-18 CN claimed
US-20050175755-A1 Process for production of aspartyl dipeptide ester derivative, novel production intermediate therefor, and process for production thereof AJINOMOTO CO., INC. (JP) 2005-08-11 US claimed
US-20040176472-A1 Process for production of aspartyl dipeptide ester derivative, novel production intermediate therefor, and process for production thereof AJINOMOTO CO., INC. (JP) 2004-09-09 US claimed
US-20020133037-A1 Process for production of aspartyl dipeptide ester derivative, novel production intermediate therefor, and process for production thereof AJINOMOTO CO. INC (JP) 2002-09-19 US claimed
EP-1231215-A1 PROCESS FOR THE PRODUCTION OF ASPARTYLDIPEPTIDE ESTER DERIVATIVES, NOVEL INTERMEDIATES THEREFOR AND PROCESS FOR THE PRODUCTION OF THE INTERMEDIATES Ajinomoto Co., Inc. (JP) 2002-08-14 EP claimed
CN-117820101-B Amplified preparation method of Edwan sweet 上海再启生物技术有限公司 2026-02-03 CN disclosed
CN-120887942-A Preparation method of Edwan sweet 宁夏万香源生物科技有限公司 2025-11-04 CN disclosed
CN-117820101-A Amplified preparation method of Edwan sweet 上海再启生物技术有限公司 2024-04-05 CN disclosed
CN-117586341-A Method for synthesizing Aide wan sweet 南通市常海食品添加剂有限公司 2024-02-23 CN disclosed
CN-115403456-B Method for synthesizing Edwan sweet intermediate 3-hydroxy-4-methoxy phenylpropionaldehyde 成都大学 2023-11-17 CN disclosed
EP-1283197-A1 PROCESS FOR PRODUCING CINNAMYLALDEHYDE DERIVATIVES, USE THEREOF AND THE LIKE Ajinomoto Co., Inc. (JP) 2003-02-12 EP disclosed
US-20030009050-A1 Crystals of aspartame derivative AJINOMOTO CO. INC. (JP) 2003-01-09 US disclosed
EP-1245573-A1 ASPARTAME DERIVATIVE CRYSTALS Ajinomoto Co., Inc. (JP) 2002-10-02 EP disclosed
US-20020133037-A1 Process for production of aspartyl dipeptide ester derivative, novel production intermediate therefor, and process for production thereof AJINOMOTO CO. INC (JP) 2002-09-19 US disclosed
EP-1231215-A1 PROCESS FOR THE PRODUCTION OF ASPARTYLDIPEPTIDE ESTER DERIVATIVES, NOVEL INTERMEDIATES THEREFOR AND PROCESS FOR THE PRODUCTION OF THE INTERMEDIATES Ajinomoto Co., Inc. (JP) 2002-08-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020133037-A1 Process for production of aspartyl dipeptide ester derivative, novel production intermediate therefor, and process for production thereof DPP4, DNPEP, IAPP CYP1A2 4465/4885CYP3A4 1255/4885TSHR 4561/4885
US-20030009050-A1 Crystals of aspartame derivative DNPEP, TASP1, DPP4 CYP1A2 4569/4885CYP3A4 1874/4885TSHR 4385/4885
US-20040176472-A1 Process for production of aspartyl dipeptide ester derivative, novel production intermediate therefor, and process for production thereof DPP4, DNPEP, IAPP CYP1A2 4465/4885CYP3A4 1255/4885TSHR 4561/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.