Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 6/20 | 0.44 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.43 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9099636 | 1.00 | AGTR1 (0.44) | AGTR1LTB4R2AGTR2 | |
| SCHEMBL7016997 | 0.81 | AGTR1 (0.46) | AGTR1LTB4R2 | |
| SCHEMBL7020280 | 0.73 | AGTR1 (0.46) | AGTR1LTB4R2 | |
| SCHEMBL7023331 | 0.70 | AGTR1 (0.48) | AGTR1 | |
| SCHEMBL7017865 | 0.68 | AGTR1 (0.48) | AGTR1LTB4R2AGTR2 | |
| SCHEMBL7017797 | 0.68 | AGTR1 (0.46) | AGTR1LTB4R2 | |
| SCHEMBL7020436 | 0.67 | AGTR1 (0.47) | AGTR1LTB4R2AGTR2 | |
| SCHEMBL7017110 | 0.67 | AGTR1 (0.48) | AGTR1LTB4R2AGTR2 | |
| SCHEMBL7019881 | 0.67 | AGTR1 (0.46) | AGTR1LTB4R2AGTR2 | |
| SCHEMBL7020676 | 0.67 | AGTR1 (0.46) | AGTR1LTB4R2AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5556981-A | Angiotensin II antagonist intermediates | ELI LILLY AND COMPANY (US) | 1996-09-17 | — | — | US | disclosed |