Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 3/20 | 0.68 |
| ▸ | PGR | P06401 | 1/20 | 0.65 |
| ▸ | MAOB | P27338 | 2/20 | 0.57 |
| ▸ | MAOA | P21397 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 10/20 | 0.55 |
| ▸ | MEN1 | O00255 | 8/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | HTT | P42858 | 4/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | USP2 | O75604 | 4/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | STS | P08842 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 4/20 | 0.54 |
| ▸ | ACHE | P22303 | 1/20 | 0.54 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9098563 | 0.92 | PGR (0.60) | CYP19A1PGRMAOBMAOAMAPT | |
| SCHEMBL13869250 | 0.89 | CYP19A1 (0.86) | CYP19A1PGRMAOBMAPTMEN1 | |
| SCHEMBL13869303 | 0.88 | CYP19A1 (0.83) | CYP19A1PGRMAOBMAPTMEN1 | |
| SCHEMBL11379521 | 0.87 | PGR (0.61) | CYP19A1PGRMAOBMAOAMAPT | |
| SCHEMBL13870275 | 0.86 | CYP19A1 (0.81) | CYP19A1PGRMAOBMAPTMEN1 | |
| SCHEMBL13870251 | 0.86 | CYP19A1 (0.81) | CYP19A1PGRMAOBMAPTMEN1 | |
| SCHEMBL13869498 | 0.85 | CYP19A1 (0.79) | CYP19A1PGRMAOBMAPTMEN1 | |
| SCHEMBL9427058 | 0.85 | PGR (0.53) | CYP19A1PGRMAOBMAOAMAPT | |
| SCHEMBL11207290 | 0.84 | CYP19A1 (0.77) | CYP19A1MAOBMAPTMEN1KMT2A | |
| SCHEMBL13869506 | 0.84 | CYP19A1 (0.86) | CYP19A1MAOBMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0428939-B1 | Cumarin derivatives, process for their preparation, their use and thiazolylacetic acid derivatives as intermediate | BAYER AG (DE) | 1996-01-17 | — | — | EP | disclosed |
| US-5300656-A | Immunoassay | BAYER AKTIENGESELLSCHAFT (DE) | 1994-04-05 | — | — | US | disclosed |
| EP-0428939-A2 | Cumarin derivatives, process for their preparation, their use and thiazolylacetic acid derivatives as intermediate | BAYER AG (DE) | 1991-05-29 | — | — | EP | disclosed |