SCHEMBL9099989

SCHEMBL9099989

COc1cncc(Cl)c1C(=O)NN(C(=O)c1cccc(O)c1C)C(C)(C)C

nearest known ligand 0.57

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ABCB1 P08183 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5056870 0.92 ABCB1 (0.52) ABCB1
SCHEMBL5064271 0.82 ABCB1 (0.55) ABCB1
SCHEMBL9101505 0.78 ABCB1 (0.58) ABCB1
SCHEMBL5064015 0.74 ABCB1 (0.71) ABCB1
SCHEMBL5058394 0.71 ABCB1 (0.64) ABCB1
SCHEMBL9102771 0.71 ABCB1 (0.64) ABCB1
SCHEMBL7701546 0.70 ABCB1 (0.71) ABCB1
SCHEMBL5062603 0.70 ABCB1 (0.55) ABCB1
SCHEMBL10720173 0.69 ABCB1 (0.64) ABCB1
SCHEMBL8998827 0.69 ABCB1 (0.67) ABCB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2460786-B1 Bioavailable diacylhydrazine ligands for modulating the expression of exogenous genes via an ecdysone receptor complex INTREXON CORP (US) 2016-01-13 EP disclosed
EP-2460786-A1 Bioavailable diacylhydrazine ligands for modulating the expression of exogenous genes via an ecdysone receptor complex Intrexon Corporation (US) 2012-06-06 EP disclosed