Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | GPX4 | P36969 | 1/20 | 0.35 |
| ▸ | PLK1 | P53350 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17424962 | 0.88 | ABCB1 (0.42) | ABCB1PLK1 | |
| SCHEMBL668808 | 0.86 | ABCB1 (0.41) | ABCB1NPC1MAPTRAB9A | |
| SCHEMBL668714 | 0.85 | ABCB1 (0.55) | ABCB1PLK1 | |
| SCHEMBL668088 | 0.81 | ABCB1 (0.53) | ABCB1PLK1 | |
| SCHEMBL668264 | 0.81 | ABCB1 (0.51) | ABCB1PLK1 | |
| SCHEMBL5053915 | 0.78 | ABCB1 (0.43) | ABCB1SMN1; SMN2 | |
| SCHEMBL5057404 | 0.77 | ABCB1 (0.57) | ABCB1NPC1MAPTRAB9A | |
| SCHEMBL667668 | 0.77 | ABCB1 (0.39) | ABCB1NPC1TSHRRAB9ASMN1; SMN2 | |
| SCHEMBL668764 | 0.77 | ABCB1 (0.57) | ABCB1 | |
| SCHEMBL5062349 | 0.77 | CYP3A4 (0.46) | ABCB1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2460786-A1 | Bioavailable diacylhydrazine ligands for modulating the expression of exogenous genes via an ecdysone receptor complex | Intrexon Corporation (US) | 2012-06-06 | — | — | EP | disclosed |