Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | ATP4A | P20648 | 7/20 | 0.43 |
| ▸ | ATP4B | P51164 | 7/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4655600 | 0.94 | KMT2A (0.48) | KMT2AMAPTMEN1PTPN2PTPN1 | |
| SCHEMBL4655485 | 0.88 | KMT2A (0.50) | KMT2AMAPTMEN1PTPN2PTPN1 | |
| SCHEMBL5424455 | 0.87 | KMT2A (0.48) | KMT2AMAPTMEN1PTPN2PTPN1 | |
| SCHEMBL4655643 | 0.86 | MAPK14 (0.52) | KMT2AMAPTMEN1ATP4AATP4B | |
| SCHEMBL4656600 | 0.86 | MAPK14 (0.52) | KMT2AMAPTMEN1ATP4AATP4B | |
| SCHEMBL5426480 | 0.86 | MAPK14 (0.52) | KMT2AMAPTMEN1ATP4AATP4B | |
| SCHEMBL5424594 | 0.81 | KMT2A (0.42) | KMT2AMAPTMEN1LMNAMAPK1 | |
| SCHEMBL4655525 | 0.79 | POLB (0.41) | KMT2AMAPTMEN1ATP4AATP4B | |
| SCHEMBL5427749 | 0.78 | MAPT (0.40) | KMT2AMAPTMEN1LMNAMAPK1 | |
| SCHEMBL5424346 | 0.78 | L3MBTL1 (0.46) | KMT2AMAPTMEN1ATP4AATP4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2460800-A1 | Substituted aminothiazole derivatives with anti-HCV activity | Achillion Pharmaceuticals, Inc. (US) | 2012-06-06 | — | — | EP | claimed |