Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 8/20 | 0.54 |
| ▸ | TRIM24 | O15164 | 3/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 8/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.33 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8553346 | 0.91 | ALOX5 (0.46) | ALOX5TRIM24CYP11B2CYP11B1CYP1A2 | |
| SCHEMBL9280770 | 0.89 | ALOX5 (0.58) | ALOX5TRIM24CYP11B2CYP11B1CYP1A2 | |
| SCHEMBL9280765 | 0.89 | ALOX5 (0.58) | ALOX5TRIM24CYP11B2CYP11B1CYP1A2 | |
| SCHEMBL9100476 | 0.89 | ALOX5 (0.58) | ALOX5TRIM24CYP11B2CYP11B1CYP1A2 | |
| SCHEMBL9280772 | 0.89 | ALOX5 (0.58) | ALOX5TRIM24CYP11B2CYP11B1CYP1A2 | |
| SCHEMBL9274972 | 0.85 | ALOX5 (0.43) | ALOX5TRIM24CYP11B2CYP11B1CYP1A2 | |
| SCHEMBL2107548 | 0.85 | ALOX5 (0.43) | ALOX5TRIM24CYP11B2CYP11B1CYP1A2 | |
| SCHEMBL9271466 | 0.85 | ALOX5 (0.45) | ALOX5TRIM24CYP11B2CYP11B1CYP1A2 | |
| SCHEMBL9275295 | 0.85 | ALOX5 (0.45) | ALOX5TRIM24CYP11B2CYP11B1CYP1A2 | |
| SCHEMBL9230759 | 0.83 | ALOX5 (0.41) | ALOX5TRIM24CYP11B2CYP11B1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0702680-A1 | 2-OXO-1,2,3,4-TETRAHYDROQUINOLINE DERIVATIVES | ZENECA LIMITED (GB) | 1996-03-27 | — | — | EP | disclosed |
| WO-1994029297-A1 | 2-OXO-1,2,3,4-TETRAHYDROQUINOLINE DERIVATIVES | ZENECA LIMITED (GB) | 1994-12-22 | — | — | WO | disclosed |