Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5062182 | 0.96 | HPGD (0.41) | HPGDSMN1; SMN2ABCB1CYP3A4NR1H2 | |
| SCHEMBL5058572 | 0.91 | HPGD (0.40) | HPGDSMN1; SMN2ABCB1CYP3A4 | |
| SCHEMBL9102918 | 0.89 | HPGD (0.37) | HPGDSMN1; SMN2ABCB1CYP3A4 | |
| SCHEMBL5056861 | 0.87 | HPGD (0.37) | HPGDSMN1; SMN2ABCB1CYP3A4 | |
| SCHEMBL5057398 | 0.86 | ABCB1 (0.44) | ABCB1 | |
| SCHEMBL5053791 | 0.84 | ABCB1 (0.39) | ABCB1 | |
| SCHEMBL5057019 | 0.82 | HPGD (0.43) | HPGDSMN1; SMN2ABCB1CYP3A4 | |
| SCHEMBL8998876 | 0.79 | ABCB1 (0.57) | ABCB1CYP3A4 | |
| SCHEMBL5057464 | 0.79 | CTNNB1 (0.47) | SMN1; SMN2ABCB1 | |
| SCHEMBL668845 | 0.77 | ABCB1 (0.50) | ABCB1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2460786-A1 | Bioavailable diacylhydrazine ligands for modulating the expression of exogenous genes via an ecdysone receptor complex | Intrexon Corporation (US) | 2012-06-06 | — | — | EP | disclosed |