SCHEMBL8998876

SCHEMBL8998876

CCc1c(C(=O)NN(C(=O)c2cc(C)cc(C)c2)C(C)(C)C)ccc2c1OCCO2

nearest known ligand 0.62

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ABCB1 P08183 7/20 0.57
CYP3A4 P08684 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL668845 0.93 ABCB1 (0.50) ABCB1CYP3A4
SCHEMBL8998748 0.92 ABCB1 (0.57) ABCB1CYP3A4
SCHEMBL5057285 0.91 ABCB1 (0.52) ABCB1CYP3A4
SCHEMBL5057465 0.88 ABCB1 (0.48) ABCB1CYP3A4
SCHEMBL668764 0.88 ABCB1 (0.57) ABCB1CYP3A4
SCHEMBL5058457 0.87 ABCB1 (0.42) ABCB1CYP3A4
SCHEMBL5062446 0.87 ABCB1 (0.56) ABCB1CYP3A4
SCHEMBL17416635 0.85 ABCB1 (0.39) ABCB1CYP3A4
SCHEMBL667409 0.85 ABCB1 (0.39) ABCB1CYP3A4
SCHEMBL29684694 0.85 ABCB1 (0.39) ABCB1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0602794-A2 Insecticidal N'-substituted-N, N'-diacylhydrazines ROHM AND HAAS COMPANY (US) 1994-06-22 EP claimed
EP-0729953-A2 A process for producing a 2-substituted-3,4-fused heterocyclic benzoic acid ROHM AND HAAS COMPANY (US) 1996-09-04 EP disclosed
EP-0729934-A2 A process for producing a 3-alkoxy-2-(substituted)benzoic acid or an ester thereof ROHM AND HAAS COMPANY (US) 1996-09-04 EP disclosed
US-5530028-A CONTROLS INSECTS OF THE ORDER LEPIDOPTERA ROHM AND HAAS COMPANY (US) 1996-06-25 US disclosed
EP-0602794-A2 Insecticidal N'-substituted-N, N'-diacylhydrazines ROHM AND HAAS COMPANY (US) 1994-06-22 EP disclosed