Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.53 |
| ▸ | NAMPT | P43490 | 5/20 | 0.37 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL391779 | 0.87 | GPR119 (0.72) | GPR119NAMPT | |
| SCHEMBL388766 | 0.84 | GPR119 (0.65) | GPR119NAMPTUSP30CYP2C9 | |
| SCHEMBL391740 | 0.84 | GPR119 (0.65) | GPR119NAMPTUSP30CYP2C9 | |
| SCHEMBL392057 | 0.83 | GPR119 (0.59) | GPR119NAMPTUSP30CYP2C9 | |
| SCHEMBL391510 | 0.81 | GPR119 (0.54) | GPR119NAMPTUSP30 | |
| SCHEMBL391945 | 0.79 | GPR119 (0.52) | GPR119NAMPTUSP30 | |
| SCHEMBL385824 | 0.79 | GPR119 (0.51) | GPR119 | |
| SCHEMBL385825 | 0.78 | GPR119 (0.51) | GPR119NAMPTUSP30CYP2C9LMNA | |
| SCHEMBL390086 | 0.77 | GPR119 (0.50) | GPR119 | |
| SCHEMBL27747853 | 0.77 | GPR119 (0.47) | GPR119NAMPTCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8193359-B2 | G-protein coupled receptor agonists | PROSIDION LIMITED (GB) | 2012-06-05 | — | — | US | claimed |