SCHEMBL9101371

SCHEMBL9101371

CCc1cc(CC)c2c(c1)Sc1ccc(CC)cc1N2C(CC)S(=O)(=O)O

nearest known ligand 0.35

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9105532 0.89 BCHE (0.37) CYP2D6
SCHEMBL9102580 0.88 CYP2D6 (0.39) CYP2D6
SCHEMBL9102684 0.86 CYP2D6 (0.37) CYP2D6
SCHEMBL9105615 0.86
SCHEMBL9103659 0.84 METAP2 (0.31)
SCHEMBL9100134 0.82 CYP2D6 (0.46) CYP2D6
SCHEMBL9102671 0.82 RAD52 (0.32)
SCHEMBL9103772 0.78 CYP2D6 (0.31) CYP2D6
SCHEMBL9105582 0.78 RAD52 (0.32)
SCHEMBL9102602 0.78 CYP2D6 (0.41) CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8192948-B1 Chemifluorescent substrate for peroxide and peroxidase detection PIERCE BIOTECHNOLOGY, INC. (US) 2012-06-05 US disclosed
EP-0361470-B1 Method for the chemiluminescence assay of the activity of peroxidase FUJIREBIO KK (JP) 1993-12-22 EP disclosed
US-5171668-A Measuring light emitted from contacting (iso)luminol, peroxide, peroxidase activity enhancer, such as indoanilines, phenolindophenol and N-methylphenothiazine, with labeled peroxidase antibody-antigen complex FUJIREBIO INC. (JP) 1992-12-15 US disclosed
EP-0361470-A2 Method for the chemiluminescence assay of the activity of peroxidase FUJIREBIO INC. (JP) 1990-04-04 EP disclosed