Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.39 |
| ▸ | CCR4 | P51679 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3694901 | 0.88 | MAPT (0.47) | MAPTADAM17KMT2ATP53RAB9A | |
| SCHEMBL9107477 | 0.86 | MAPT (0.49) | MAPTADAM17KMT2ATP53RAB9A | |
| SCHEMBL9105309 | 0.86 | MAPT (0.47) | MAPTADAM17CCR4KMT2ATP53 | |
| SCHEMBL9107398 | 0.85 | KMT2A (0.40) | MAPK1HSD17B10KMT2ATSHRRAB9A | |
| SCHEMBL3699318 | 0.85 | MAPT (0.42) | MAPTRAB9AALDH1A1 | |
| SCHEMBL9106131 | 0.84 | KMT2A (0.41) | MAPK1HSD17B10KMT2ALIPGRAB9A | |
| SCHEMBL3694999 | 0.84 | MAPT (0.49) | MAPTADAM17KMT2ATP53RAB9A | |
| SCHEMBL9103782 | 0.84 | MAPT (0.48) | MAPTADAM17KMT2ATP53ALDH1A1 | |
| SCHEMBL9108290 | 0.83 | MAPT (0.45) | MAPTADAM17KMT2ATP53ALDH1A1 | |
| SCHEMBL3693912 | 0.83 | MAPT (0.47) | MAPTADAM17KMT2ATP53ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2460798-A2 | APAF-1 INHIBITOR COMPOUNDS | Laboratorios SALVAT, S.A. (ES) | 2012-06-06 | — | — | EP | disclosed |