Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.59 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.59 |
| ▸ | IGF1R | P08069 | 2/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.59 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.55 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.55 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.54 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.54 |
| ▸ | TACR2 | P21452 | 2/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | SHBG | P04278 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.54 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9657346 | 0.93 | ESR1 (0.63) | ESR1ESR2IGF1RALOX15ADRA2A | |
| SCHEMBL5647781 | 0.90 | ESR1 (0.74) | ESR1ESR2IGF1RALOX15ADRA2A | |
| SCHEMBL18050371 | 0.87 | TAAR1 (0.62) | IGF1RALOX15LMNAHTR3ATAAR1 | |
| SCHEMBL245139 | 0.87 | ESR1 (0.77) | ESR1ESR2IGF1RALOX15CALM1 | |
| SCHEMBL1171041 | 0.87 | ESR1 (0.77) | ESR1ESR2IGF1RALOX15CALM1 | |
| SCHEMBL10365734 | 0.82 | IGF1R (0.64) | IGF1RALOX15LMNAHTR3ATAAR1 | |
| SCHEMBL449737 | 0.82 | ESR1 (0.77) | ESR1ESR2IGF1RALOX15CALM1 | |
| SCHEMBL9460441 | 0.81 | MEN1 (0.49) | ESR1ESR2IGF1RALOX15ADRA2A | |
| SCHEMBL3155617 | 0.80 | ESR1 (0.65) | ESR1ESR2IGF1RALOX15CALM1 | |
| SCHEMBL2289447 | 0.80 | ESR1 (0.74) | ESR1ESR2NPC1RAB9ACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0712388-A1 | USE OF PHENOLS AND PHENOL DERIVATES AS MEDICAMENTS WITH FIBRINOGEN-REDUCING EFFECT | Roche Diagnostics GmbH (DE) | 1996-05-22 | — | — | EP | disclosed |
| WO-1995005358-A1 | USE OF PHENOLS AND PHENOL DERIVATES AS MEDICAMENTS WITH FIBRINOGEN-REDUCING EFFECT | BOEHRINGER MANNHEIM GMBH (DE) | 1995-02-23 | — | — | WO | disclosed |