Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.74 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5056953 | 0.95 | ABCB1 (0.76) | HPGDSMN1; SMN2ABCB1CYP3A4 | |
| SCHEMBL1045829 | 0.86 | ABCB1 (0.90) | HPGDSMN1; SMN2ABCB1CYP3A4 | |
| SCHEMBL18091875 | 0.86 | ABCB1 (0.76) | HPGDSMN1; SMN2ABCB1CYP3A4 | |
| SCHEMBL8423072 | 0.86 | HPGD (1.00) | HPGDSMN1; SMN2ABCB1CYP3A4 | |
| SCHEMBL10719961 | 0.85 | HPGD (0.78) | HPGDSMN1; SMN2ABCB1CYP3A4 | |
| SCHEMBL5056863 | 0.85 | ABCB1 (0.71) | HPGDSMN1; SMN2ABCB1CYP3A4 | |
| SCHEMBL9714459 | 0.85 | HPGD (0.86) | HPGDSMN1; SMN2ABCB1CYP3A4 | |
| SCHEMBL9714453 | 0.85 | HPGD (0.86) | HPGDSMN1; SMN2ABCB1CYP3A4 | |
| Hydrochloric Acid SCHEMBL8174716 | 0.84 | HPGD (0.84) | HPGDSMN1; SMN2ABCB1CYP3A4 | |
| SCHEMBL10719977 | 0.83 | HPGD (0.89) | HPGDSMN1; SMN2ABCB1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2460786-A1 | Bioavailable diacylhydrazine ligands for modulating the expression of exogenous genes via an ecdysone receptor complex | Intrexon Corporation (US) | 2012-06-06 | — | — | EP | disclosed |