Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 6/20 | 0.90 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.90 |
| ▸ | HPGD | P15428 | 1/20 | 0.80 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.80 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tebufenozide SCHEMBL64845 | 0.95 | ABCB1 (1.00) | ABCB1CYP3A4HPGDSMN1; SMN2 | |
| SCHEMBL18091875 | 0.92 | ABCB1 (0.76) | ABCB1CYP3A4HPGDSMN1; SMN2 | |
| SCHEMBL10719977 | 0.89 | HPGD (0.89) | ABCB1CYP3A4HPGDSMN1; SMN2 | |
| SCHEMBL8423072 | 0.89 | HPGD (1.00) | ABCB1CYP3A4HPGDSMN1; SMN2 | |
| SCHEMBL9825948 | 0.89 | ABCB1 (0.76) | ABCB1CYP3A4HPGDSMN1; SMN2 | |
| Tebufenozide SCHEMBL2126005 | 0.87 | ABCB1 (0.84) | ABCB1CYP3A4HPGDSMN1; SMN2 | |
| SCHEMBL5064091 | 0.87 | ABCB1 (0.84) | ABCB1CYP3A4HPGDSMN1; SMN2 | |
| SCHEMBL8772428 | 0.86 | ABCB1 (0.80) | ABCB1CYP3A4HPGDSMN1; SMN2 | |
| Tebufenozide SCHEMBL30211368 | 0.86 | ABCB1 (0.84) | ABCB1CYP3A4HPGDSMN1; SMN2 | |
| SCHEMBL9101628 | 0.86 | HPGD (0.74) | ABCB1CYP3A4HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 117 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6277867-B1 | SYNERGISTIC MIXTURES | CHINOIN GYOGYSZER ES VEGYESZETI (HU) | 2001-08-21 | — | — | US | claimed |
| US-6123756-A | FOR PROTECTION OF WOOD AGAINST DESTRUCTION AND QUALITY IMPAIRMENT DUE TO ATTACK BY INJURIOUS ORGANISMS SUCH AS INSECTS AND FUNGI | REMMERS BAUCHEMINE GMBH (DE) | 2000-09-26 | — | — | US | claimed |
| EP-0736252-A2 | Synergistic compositions with diafenthiuron | CIBA-GEIGY AG (CH) | 1996-10-09 | — | — | EP | claimed |
| US-11116852-B2 | Frataxin expression constructs | PRECIGEN, INC. (US) | 2021-09-14 | — | — | US | disclosed |
| US-20200239906-A1 | VECTORS CONDITIONALLY EXPRESSING THERAPEUTIC PROTEINS, HOST CELLS COMPRISING THE VECTORS, AND USES THEREOF | INTREXON CORP (US) | 2020-07-30 | — | — | US | disclosed |
| EP-3470520-A2 | NOVEL SUBSTITUTION MUTANT RECEPTORS AND THEIR USE IN A NUCLEAR RECEPTOR-BASED INDUCIBLE GENE EXPRESSION SYSTEM | Intrexon Corporation (US) | 2019-04-17 | — | — | EP | disclosed |
| US-10190124-B2 | Substitution mutant receptors and their use in a nuclear receptor-based inducible gene expression system | INTREXON CORPORATION (US) | 2019-01-29 | — | — | US | disclosed |
| EP-2275558-B1 | Novel substitution mutant receptors and their use in a nuclear receptor-based inducible gene expression system | INTREXON CORP (US) | 2018-11-28 | — | — | EP | disclosed |
| US-20180213776-A1 | COMPOSITIONS FOR CONTROLLING MOSQUITO POPULATIONS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2018-08-02 | — | — | US | disclosed |
| US-20180213776-A1 | COMPOSITIONS FOR CONTROLLING MOSQUITO POPULATIONS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2018-08-02 | — | — | US | disclosed |
| US-20180140721-A1 | FRATAXIN EXPRESSION CONSTRUCTS | INTREXON CORPORATION (US) | 2018-05-24 | — | — | US | disclosed |
| WO-1997027173-A2 | DIHALOPROPENE COMPOUNDS, THEIR USE AS INSECTICIDES/ACARICIDES AND INTERMEDIATES FOR THEIR PRODUCTION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-31 | — | — | WO | disclosed |
| EP-0736252-A2 | Synergistic compositions with diafenthiuron | CIBA-GEIGY AG (CH) | 1996-10-09 | — | — | EP | disclosed |
| US-5563174-A | LOW TOXICITY TO MAMMALS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1996-10-08 | — | — | US | disclosed |
| EP-0722430-A1 | DIHALOPROPENE COMPOUNDS, INSECTICIDAL/ACARICIDAL AGENTS CONTAINING SAME, AND INTERMEDIATES FOR THEIR PRODUCTION | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-07-24 | — | — | EP | disclosed |
| WO-1996004228-A1 | DIHALOPROPENE COMPOUNDS, INSECTICIDAL/ACARICIDAL AGENTS CONTAINING SAME, AND INTERMEDIATES FOR THEIR PRODUCTION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1996-02-15 | — | — | WO | disclosed |
| EP-0461809-B1 | Dibenzoylalkylcyanohydrazines | ROHM & HAAS (US) | 1994-12-07 | — | — | EP | disclosed |
| EP-0245950-B1 | INSECTICIDAL N-SUBSTITUTED-N' - SUBSTITUTED-N, N'-DIACYLHYDRAZINES | ROHM AND HAAS COMPANY (US) | 1992-06-17 | — | — | EP | disclosed |
| EP-0461809-A1 | Dibenzoylalkylcyanohydrazines | ROHM AND HAAS COMPANY (US) | 1991-12-18 | — | — | EP | disclosed |
| EP-0236618-A2 | Insecticidal N'-substituted-N,N'-diacylhydrazines | ROHM AND HAAS COMPANY (US) | 1987-09-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180213776-A1 | COMPOSITIONS FOR CONTROLLING MOSQUITO POPULATIONS | CYP46A1, CYP17A1, CYP11A1 | ABCB1 3055/4885CYP3A4 179/4885HPGD 1011/4885 |
| US-20200239906-A1 | VECTORS CONDITIONALLY EXPRESSING THERAPEUTIC PROTEINS, HOST CELLS COMPRISING THE VECTORS, AND USES THEREOF | HAVCR2, CD74, CD40 | ABCB1 2389/4885CYP3A4 4843/4885HPGD 2590/4885 |
| US-10190124-B2 | Substitution mutant receptors and their use in a nuclear receptor-based inducible gene expression system | NR2E3, NR1H4, NR1H3 | ABCB1 932/4885CYP3A4 1992/4885HPGD 1715/4885 |
| US-20180140721-A1 | FRATAXIN EXPRESSION CONSTRUCTS | ATXN10, ATXN2, FERMT2 | ABCB1 2734/4885CYP3A4 4857/4885HPGD 4224/4885 |
| US-11116852-B2 | Frataxin expression constructs | ATXN10, ATXN2, FERMT2 | ABCB1 2734/4885CYP3A4 4857/4885HPGD 4224/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.