SCHEMBL9102006

SCHEMBL9102006

CCCS(=O)(=O)ON1c2cccc(C)c2Oc2cc(C)cc(C)c21

nearest known ligand 0.31

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
NR3C1 P04150 2/20 0.31
RAPGEF4 Q8WZA2 1/20 0.31
CA12 O43570 1/20 0.30
CA2 P00918 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9105403 0.89 TSHR (0.32)
SCHEMBL9100107 0.87 NR3C1 (0.32) NR3C1CA12CA2
SCHEMBL9105473 0.87 P2RX4 (0.38) CA12CA2
SCHEMBL9105106 0.86 KDM4E (0.31) RAPGEF4
SCHEMBL9100971 0.83 P2RX4 (0.35)
SCHEMBL9103810 0.83 CA12 (0.31) CA12CA2
SCHEMBL9103595 0.81 P2RX4 (0.35) CA12CA2
SCHEMBL9104365 0.80 P2RX4 (0.38)
SCHEMBL9104611 0.78 P2RX4 (0.35)
SCHEMBL9100000 0.76 NR3C1 (0.31) NR3C1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8192948-B1 Chemifluorescent substrate for peroxide and peroxidase detection PIERCE BIOTECHNOLOGY, INC. (US) 2012-06-05 US disclosed
EP-0361470-B1 Method for the chemiluminescence assay of the activity of peroxidase FUJIREBIO KK (JP) 1993-12-22 EP disclosed
US-5171668-A Measuring light emitted from contacting (iso)luminol, peroxide, peroxidase activity enhancer, such as indoanilines, phenolindophenol and N-methylphenothiazine, with labeled peroxidase antibody-antigen complex FUJIREBIO INC. (JP) 1992-12-15 US disclosed
EP-0361470-A2 Method for the chemiluminescence assay of the activity of peroxidase FUJIREBIO INC. (JP) 1990-04-04 EP disclosed