Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 3/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | PIM1 | P11309 | 2/20 | 0.39 |
| ▸ | P2RX4 | Q99571 | 3/20 | 0.38 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | MMP13 | P45452 | 2/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9103979 | 0.94 | SMPD1 (0.43) | SMPD1SIGMAR1MEN1KMT2ATDP1 | |
| SCHEMBL9104003 | 0.93 | MEN1 (0.43) | SMPD1SIGMAR1MEN1KMT2ATDP1 | |
| SCHEMBL9100252 | 0.92 | S1PR2 (0.36) | SMPD1SIGMAR1MEN1KMT2ATDP1 | |
| SCHEMBL9103976 | 0.90 | SIGMAR1 (0.42) | SMPD1SIGMAR1MEN1KMT2ATDP1 | |
| SCHEMBL9107625 | 0.88 | MEN1 (0.44) | SMPD1SIGMAR1MEN1KMT2ATDP1 | |
| SCHEMBL9102589 | 0.86 | S1PR2 (0.35) | SMPD1SIGMAR1MEN1KMT2ATDP1 | |
| SCHEMBL9101887 | 0.86 | PIM1 (0.35) | SMPD1SIGMAR1MEN1KMT2ATDP1 | |
| SCHEMBL9103912 | 0.85 | SIGMAR1 (0.37) | SMPD1SIGMAR1MEN1KMT2ATDP1 | |
| SCHEMBL9105611 | 0.84 | SIGMAR1 (0.38) | SMPD1SIGMAR1MEN1KMT2ATDP1 | |
| SCHEMBL182696 | 0.83 | SIGMAR1 (0.46) | SMPD1SIGMAR1MEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8192948-B1 | Chemifluorescent substrate for peroxide and peroxidase detection | PIERCE BIOTECHNOLOGY, INC. (US) | 2012-06-05 | — | — | US | disclosed |
| EP-0361470-B1 | Method for the chemiluminescence assay of the activity of peroxidase | FUJIREBIO KK (JP) | 1993-12-22 | — | — | EP | disclosed |
| US-5171668-A | Measuring light emitted from contacting (iso)luminol, peroxide, peroxidase activity enhancer, such as indoanilines, phenolindophenol and N-methylphenothiazine, with labeled peroxidase antibody-antigen complex | FUJIREBIO INC. (JP) | 1992-12-15 | — | — | US | disclosed |
| EP-0361470-A2 | Method for the chemiluminescence assay of the activity of peroxidase | FUJIREBIO INC. (JP) | 1990-04-04 | — | — | EP | disclosed |