Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11870858 | 0.98 | RAB9A (0.46) | RAB9ATP53HDAC4HDAC2HDAC8 | |
| SCHEMBL3700324 | 0.98 | RAB9A (0.46) | RAB9ATP53HDAC4HDAC2HDAC8 | |
| Hydrochloric Acid SCHEMBL11871911 | 0.98 | RAB9A (0.46) | RAB9ATP53HDAC4HDAC2HDAC8 | |
| SCHEMBL11879078 | 0.96 | RAB9A (0.44) | RAB9ATP53HDAC4HDAC2HDAC8 | |
| SCHEMBL3702604 | 0.92 | TP53 (0.47) | RAB9ATP53HDAC4HDAC2HDAC8 | |
| SCHEMBL28330036 | 0.86 | — | — | |
| Hydrochloric Acid SCHEMBL11871905 | 0.84 | HDAC4 (0.38) | RAB9ATP53HDAC4HDAC2HDAC8 | |
| SCHEMBL11870851 | 0.81 | HDAC4 (0.39) | RAB9AHDAC4HDAC2HDAC8HDAC6 | |
| SCHEMBL11874913 | 0.81 | HDAC4 (0.39) | RAB9AHDAC4HDAC2HDAC8HDAC6 | |
| SCHEMBL11871053 | 0.80 | HDAC4 (0.38) | RAB9AHDAC4HDAC2HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5550110-A | PENTAPEPTIDE AND HEXAPEPTIDE ANALOGS OF ENDOTHELIN-1 | WARNER-LAMBERT COMPANY (US) | 1996-08-27 | — | — | US | disclosed |