Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.57 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.57 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.57 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29827751 | 0.83 | CYP3A4 (0.62) | TAAR1SLC6A4SLC6A2SLC6A3CYP3A4 | |
| SCHEMBL1739571 | 0.83 | CYP3A4 (0.62) | TAAR1SLC6A4SLC6A2SLC6A3CYP3A4 | |
| SCHEMBL217047 | 0.83 | CYP3A4 (0.62) | TAAR1SLC6A4SLC6A2SLC6A3CYP3A4 | |
| Hydrochloric Acid SCHEMBL31545549 | 0.82 | CYP3A4 (0.61) | TAAR1SLC6A4SLC6A2SLC6A3CYP3A4 | |
| Tenamfetamine SCHEMBL9102090 | 0.81 | SLC6A4 (0.53) | TAAR1SLC6A4SLC6A2SLC6A3CYP3A4 | |
| SCHEMBL28599105 | 0.77 | TAAR1 (0.53) | TAAR1SLC6A4SLC6A2SLC6A3CYP3A4 | |
| Hydrochloric Acid SCHEMBL28591709 | 0.76 | TAAR1 (0.52) | TAAR1SLC6A4SLC6A2SLC6A3CYP3A4 | |
| Tenamfetamine SCHEMBL15162053 | 0.76 | TAAR1 (1.00) | TAAR1SLC6A4SLC6A2SLC6A3CYP3A4 | |
| Tenamfetamine SCHEMBL9361151 | 0.76 | TAAR1 (1.00) | TAAR1SLC6A4SLC6A2SLC6A3CYP3A4 | |
| Tenamfetamine SCHEMBL30904507 | 0.76 | TAAR1 (1.00) | TAAR1SLC6A4SLC6A2SLC6A3CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5534492-A | Muramyl peptide for the treatment of toxicity | PEPTECH (UK) LIMITED (GB) | 1996-07-09 | — | — | US | disclosed |
| WO-1993016713-A2 | USE OF MURAMYL PEPTIDE FOR THE TREATMENT OF TOXICITY | PEPTECH (UK) LIMITED (GB) | 1993-09-02 | — | — | WO | disclosed |