Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 3/20 | 0.53 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.53 |
| ▸ | HTR2A | P28223 | 3/20 | 0.47 |
| ▸ | HTR2C | P28335 | 3/20 | 0.47 |
| ▸ | HTR2B | P41595 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | DRD1 | P21728 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tenamfetamine SCHEMBL9102083 | 0.81 | TAAR1 (0.57) | SLC6A4TAAR1SLC6A2SLC6A3GAA | |
| SCHEMBL217047 | 0.80 | CYP3A4 (0.62) | SLC6A4TAAR1SLC6A2SLC6A3GAA | |
| SCHEMBL1739571 | 0.80 | CYP3A4 (0.62) | SLC6A4TAAR1SLC6A2SLC6A3GAA | |
| SCHEMBL29827751 | 0.80 | CYP3A4 (0.62) | SLC6A4TAAR1SLC6A2SLC6A3GAA | |
| Hydrochloric Acid SCHEMBL31545549 | 0.79 | CYP3A4 (0.61) | SLC6A4TAAR1SLC6A2SLC6A3GAA | |
| Tenamfetamine SCHEMBL9361151 | 0.73 | TAAR1 (1.00) | SLC6A4TAAR1SLC6A2SLC6A3GAA | |
| Tenamfetamine SCHEMBL393456 | 0.73 | TAAR1 (1.00) | SLC6A4TAAR1SLC6A2SLC6A3GAA | |
| Tenamfetamine SCHEMBL15162053 | 0.73 | TAAR1 (1.00) | SLC6A4TAAR1SLC6A2SLC6A3GAA | |
| Tenamfetamine SCHEMBL30904507 | 0.73 | TAAR1 (1.00) | SLC6A4TAAR1SLC6A2SLC6A3GAA | |
| Tenamfetamine SCHEMBL29392330 | 0.73 | TAAR1 (1.00) | SLC6A4TAAR1SLC6A2SLC6A3GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5534492-A | Muramyl peptide for the treatment of toxicity | PEPTECH (UK) LIMITED (GB) | 1996-07-09 | — | — | US | disclosed |
| WO-1993016713-A2 | USE OF MURAMYL PEPTIDE FOR THE TREATMENT OF TOXICITY | PEPTECH (UK) LIMITED (GB) | 1993-09-02 | — | — | WO | disclosed |