SCHEMBL9102178

SCHEMBL9102178

CCCS(=O)(=O)ON1c2ccc(CC)cc2Sc2c(CC)cccc21

nearest known ligand 0.30

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.30
ALDH1A1 P00352 1/20 0.30
F2 P00734 1/20 0.30
MAPT P10636 1/20 0.30
VDR P11473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9104980 0.89
SCHEMBL9107719 0.87 LMNA (0.31)
SCHEMBL9103401 0.87 BCHE (0.35) KDM4EMAPT
SCHEMBL9102618 0.86 CYP2D6 (0.39) KDM4EALDH1A1F2MAPTVDR
SCHEMBL9102690 0.86
SCHEMBL9102705 0.82 CYP2D6 (0.35) KDM4EALDH1A1F2MAPTVDR
SCHEMBL9104032 0.81 RAD52 (0.32)
SCHEMBL9101568 0.81 HTT (0.33) KDM4EALDH1A1F2MAPTVDR
SCHEMBL9104584 0.81 BCHE (0.34) KDM4EMAPT
SCHEMBL9100150 0.79 CYP2D6 (0.44) KDM4EALDH1A1F2MAPTVDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8192948-B1 Chemifluorescent substrate for peroxide and peroxidase detection PIERCE BIOTECHNOLOGY, INC. (US) 2012-06-05 US disclosed
EP-0361470-B1 Method for the chemiluminescence assay of the activity of peroxidase FUJIREBIO KK (JP) 1993-12-22 EP disclosed
US-5171668-A Measuring light emitted from contacting (iso)luminol, peroxide, peroxidase activity enhancer, such as indoanilines, phenolindophenol and N-methylphenothiazine, with labeled peroxidase antibody-antigen complex FUJIREBIO INC. (JP) 1992-12-15 US disclosed
EP-0361470-A2 Method for the chemiluminescence assay of the activity of peroxidase FUJIREBIO INC. (JP) 1990-04-04 EP disclosed