Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 2/20 | 0.51 |
| ▸ | MAOA | P21397 | 5/20 | 0.49 |
| ▸ | MGAM | O43451 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | SI | P14410 | 1/20 | 0.47 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | KDM5A | P29375 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1179868 | 0.76 | MAOA (0.52) | MAOAMGAMGAASIMGAM2 | |
| SCHEMBL21075000 | 0.76 | MAOA (0.52) | MAOAMGAMGAASIMGAM2 | |
| SCHEMBL9778972 | 0.75 | KDM4E (0.45) | ERN1MAOAMGAMGAASI | |
| SCHEMBL1163384 | 0.74 | KDM4E (0.51) | ERN1MAOAMGAMGAASI | |
| SCHEMBL4737860 | 0.73 | KDM5A (0.59) | MAOAGAAKDM4EKDM5ACA12 | |
| SCHEMBL3874433 | 0.73 | MAOA (0.49) | MAOAMGAMGAASIMGAM2 | |
| SCHEMBL20836043 | 0.73 | MAOA (0.49) | MAOAMGAMGAASIMGAM2 | |
| SCHEMBL8112121 | 0.73 | MAOA (0.51) | MAOAMGAMGAASIMGAM2 | |
| SCHEMBL16609363 | 0.73 | MAOA (0.49) | MAOAMGAMGAASIMGAM2 | |
| SCHEMBL5306184 | 0.73 | MAOA (0.49) | MAOAMGAMGAASIMGAM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5552091-A | PHOTOCHROMIC, LENSES | PPG INDUSTRIES, INC. (US) | 1996-09-03 | — | — | US | disclosed |
| WO-1994020869-A1 | NOVEL BENZOPYRANS | PPG INDUSTRIES, INC. (US) | 1994-09-15 | — | — | WO | disclosed |