SCHEMBL9102522

SCHEMBL9102522

Cc1ccc2cc(C(=O)O)ccc2n1.Cc1ccc2nc(C)ccc2c1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.68
TDP1 Q9NUW8 2/20 0.51
MEN1 O00255 4/20 0.51
KMT2A Q03164 4/20 0.51
ALDH1A1 P00352 3/20 0.51
KDM4E B2RXH2 2/20 0.51
GAA P10253 2/20 0.51
MAPT P10636 1/20 0.51
HPGD P15428 1/20 0.51
NPC1 O15118 5/20 0.50
RAB9A P51151 5/20 0.50
CYP2A6 P11509 1/20 0.49
HSD17B14 Q9BPX1 1/20 0.47
HSP90AA1 P07900 1/20 0.46
ESR2 Q92731 1/20 0.46
LMNA P02545 2/20 0.46
NCK1 P16333 1/20 0.46
BACE1 P56817 1/20 0.46
POLB P06746 1/20 0.46
CASP6 P55212 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30464299 0.93 TDP1 (0.58) CYP1A2TDP1MEN1KMT2AALDH1A1
SCHEMBL999160 0.93 TDP1 (0.58) CYP1A2TDP1MEN1KMT2AALDH1A1
Hydrochloric Acid SCHEMBL1000350 0.92 TDP1 (0.56) CYP1A2TDP1MEN1KMT2AALDH1A1
Hydrochloric Acid SCHEMBL16621042 0.92 TDP1 (0.56) CYP1A2TDP1MEN1KMT2AALDH1A1
SCHEMBL2614267 0.82 CYP2A6 (0.62) CYP1A2TDP1ALDH1A1KDM4EGAA
SCHEMBL31129157 0.82 CYP2A6 (0.62) CYP1A2TDP1ALDH1A1KDM4EGAA
SCHEMBL9099287 0.82 CYP2A6 (0.62) CYP1A2TDP1ALDH1A1KDM4EGAA
SCHEMBL29444268 0.82 CYP1A2 (1.00) CYP1A2TDP1MEN1KMT2AALDH1A1
SCHEMBL161703 0.82 CYP1A2 (1.00) CYP1A2TDP1MEN1KMT2AALDH1A1
SCHEMBL6880429 0.81 TDP1 (0.59) CYP1A2TDP1MEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0707656-A1 BIOTECHNOLOGICAL PROCESS FOR PRODUCING ALCOHOLS, ALDEHYDES AND CARBOXYLIC ACIDS BASF AKTIENGESELLSCHAFT (DE) 1996-04-24 EP disclosed
WO-1995002061-A1 BIOTECHNOLOGICAL PROCESS FOR PRODUCING ALCOHOLS, ALDEHYDES AND CARBOXYLIC ACIDS BASF AKTIENGESELLSCHAFT (DE) 1995-01-19 WO disclosed