Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 8/20 | 0.55 |
| ▸ | RAB9A | P51151 | 8/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | CASP6 | P55212 | 1/20 | 0.52 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.51 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.45 |
| ▸ | VNN1 | O95497 | 1/20 | 0.44 |
| ▸ | MGAM | O43451 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL999160 | 1.00 | TDP1 (0.58) | TDP1NPC1RAB9ACYP1A2MEN1 | |
| Hydrochloric Acid SCHEMBL16621042 | 0.98 | TDP1 (0.56) | TDP1NPC1RAB9ACYP1A2MEN1 | |
| Hydrochloric Acid SCHEMBL1000350 | 0.98 | TDP1 (0.56) | TDP1NPC1RAB9ACYP1A2MEN1 | |
| SCHEMBL9102522 | 0.93 | CYP1A2 (0.68) | TDP1NPC1RAB9ACYP1A2MEN1 | |
| SCHEMBL6880429 | 0.87 | TDP1 (0.59) | TDP1NPC1RAB9ACYP1A2MEN1 | |
| SCHEMBL31201668 | 0.85 | NPC1 (0.55) | NPC1RAB9ACYP1A2MEN1KMT2A | |
| SCHEMBL5095477 | 0.85 | NPC1 (0.55) | NPC1RAB9ACYP1A2MEN1KMT2A | |
| SCHEMBL2224282 | 0.85 | TDP1 (0.58) | TDP1NPC1RAB9ACYP1A2MEN1 | |
| SCHEMBL15286803 | 0.84 | POLB (0.55) | NPC1RAB9ACYP1A2MEN1KMT2A | |
| SCHEMBL1000348 | 0.84 | CYP1A2 (0.53) | TDP1NPC1RAB9ACYP1A2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023111005-A1 | CARBOXAMIDE SUBSTITUTED HETEROAROMATIC COMPOUNDS FOR TREATING CANCER | WMT AG (DE) | 2023-06-22 | — | — | WO | disclosed |