SCHEMBL9102583

SCHEMBL9102583

CC(C)[C@@H](CN1CCCCC1)N(C)C(=O)c1ccc(Cl)cc1

nearest known ligand 0.68

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ USP2 O75604 1/20 0.55
▸ ALOX15 P16050 1/20 0.55
▸ TSHR P16473 1/20 0.48
▸ NTSR1 P30989 1/20 0.48
▸ MCHR1 Q99705 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9273522 0.99 USP2 (0.53) USP2ALOX15TSHRMCHR1
SCHEMBL9100760 0.99 USP2 (0.53) USP2ALOX15TSHRMCHR1
SCHEMBL9100764 0.99 USP2 (0.53) USP2ALOX15TSHRMCHR1
Hydrochloric Acid SCHEMBL9100578 0.97 USP2 (0.55) USP2ALOX15NTSR1MCHR1
Hydrochloric Acid SCHEMBL9100568 0.97 USP2 (0.55) USP2ALOX15NTSR1MCHR1
Hydrochloric Acid SCHEMBL9277199 0.97 USP2 (0.55) USP2ALOX15NTSR1MCHR1
SCHEMBL9104181 0.96 USP2 (0.50) USP2ALOX15TSHRMCHR1
SCHEMBL9104187 0.96 USP2 (0.50) USP2ALOX15TSHRMCHR1
Cadaverine Tartrate SCHEMBL9278624 0.90 USP2 (0.46) USP2ALOX15NTSR1MCHR1
Cadaverine Tartrate SCHEMBL9100745 0.90 USP2 (0.46) USP2ALOX15NTSR1MCHR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025082731-A1 INTRANASAL FORMULATIONS FOR TREATING OBSTRUCTIVE SLEEP APNEA MOSANNA THERAPEUTICS AG (CH) 2025-04-24 — — WO disclosed
US-20130143858-A1 COMPOUNDS AND THEIR USE AS IKACH BLOCKERS ASTRAZENECA AB (SE) 2013-06-06 — — US disclosed
US-8361998-B2 Compounds and their use as IKACh blockers ASTRAZENECA AB 2013-01-29 — — US disclosed
WO-2012074469-A1 NEW IKACH BLOCKERS ASTRAZENECA AB (SE) 2012-06-07 — — WO disclosed
US-20120142659-A1 COMPOUNDS AND THEIR USE AS IKACH BLOCKERS ASTRAZENECA AB (SE) 2012-06-07 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130143858-A1 COMPOUNDS AND THEIR USE AS IKACH BLOCKERS KCNH2, KCNJ2, KCNH3 USP2 3248/4885ALOX15 4547/4885TSHR 304/4885
US-20120142659-A1 COMPOUNDS AND THEIR USE AS IKACH BLOCKERS KCNH2, KCNJ2, KCNH3 USP2 3248/4885ALOX15 4547/4885TSHR 304/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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