SCHEMBL9102611

SCHEMBL9102611

CCCS(=O)(=O)ON1c2ccccc2Oc2cccc(-c3ncccc3Cl)c21

nearest known ligand 0.35

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
TDP2 O95551 1/20 0.32
DPP4 P27487 1/20 0.31
LIMK1 P53667 1/20 0.31
NFE2L2 Q16236 1/20 0.30
SMO Q99835 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9103550 0.89 MEN1 (0.31) MEN1KMT2ASMO
SCHEMBL9104689 0.89 SGMS2 (0.32) MEN1KMT2A
SCHEMBL9100373 0.88 CA1 (0.32) MEN1KMT2A
SCHEMBL9106488 0.87 MEN1 (0.30) MEN1KMT2A
SCHEMBL9101867 0.86 NR1H2 (0.32)
SCHEMBL9106101 0.84 P2RX4 (0.36) MEN1KMT2A
SCHEMBL9101795 0.83 BCHE (0.35) MEN1KMT2ADPP4LIMK1
SCHEMBL9101809 0.82 USP2 (0.31)
SCHEMBL9100730 0.80 P2RX1 (0.31)
SCHEMBL9102910 0.79 P2RX4 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8192948-B1 Chemifluorescent substrate for peroxide and peroxidase detection PIERCE BIOTECHNOLOGY, INC. (US) 2012-06-05 US disclosed
EP-0361470-B1 Method for the chemiluminescence assay of the activity of peroxidase FUJIREBIO KK (JP) 1993-12-22 EP disclosed
US-5171668-A Measuring light emitted from contacting (iso)luminol, peroxide, peroxidase activity enhancer, such as indoanilines, phenolindophenol and N-methylphenothiazine, with labeled peroxidase antibody-antigen complex FUJIREBIO INC. (JP) 1992-12-15 US disclosed
EP-0361470-A2 Method for the chemiluminescence assay of the activity of peroxidase FUJIREBIO INC. (JP) 1990-04-04 EP disclosed