SCHEMBL9102641

SCHEMBL9102641

CCCS(=O)(=O)ON1c2ccccc2Oc2cccc(Br)c21

nearest known ligand 0.36

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
P2RX4 Q99571 11/20 0.36
P2RX1 P51575 2/20 0.36
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
P2RX3 P56373 1/20 0.31
MAPT P10636 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
PDE4B Q07343 1/20 0.31
RXFP1 Q9HBX9 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9103893 0.89 P2RX4 (0.33) P2RX4P2RX1MEN1KMT2ARXFP1
SCHEMBL9101934 0.86 P2RX4 (0.36) P2RX4P2RX1P2RX3MAPTSMN1; SMN2
SCHEMBL9104365 0.86 P2RX4 (0.38) P2RX4P2RX1KMT2AP2RX3MAPT
SCHEMBL9104487 0.85 P2RX4 (0.41) P2RX4P2RX1MEN1KMT2AP2RX3
SCHEMBL9104489 0.85 P2RX4 (0.43) P2RX4P2RX1P2RX3
SCHEMBL9106101 0.85 P2RX4 (0.36) P2RX4P2RX1MEN1KMT2A
SCHEMBL9100373 0.84 CA1 (0.32) MEN1KMT2A
SCHEMBL9102996 0.84 P2RX4 (0.36) P2RX4P2RX1P2RX3MAPTSMN1; SMN2
SCHEMBL9104503 0.82 P2RX4 (0.35) P2RX4P2RX1
SCHEMBL9099192 0.81 AHR (0.39) P2RX4P2RX1MEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8192948-B1 Chemifluorescent substrate for peroxide and peroxidase detection PIERCE BIOTECHNOLOGY, INC. (US) 2012-06-05 US disclosed
EP-0361470-B1 Method for the chemiluminescence assay of the activity of peroxidase FUJIREBIO KK (JP) 1993-12-22 EP disclosed
US-5171668-A Measuring light emitted from contacting (iso)luminol, peroxide, peroxidase activity enhancer, such as indoanilines, phenolindophenol and N-methylphenothiazine, with labeled peroxidase antibody-antigen complex FUJIREBIO INC. (JP) 1992-12-15 US disclosed
EP-0361470-A2 Method for the chemiluminescence assay of the activity of peroxidase FUJIREBIO INC. (JP) 1990-04-04 EP disclosed