SCHEMBL9103893

SCHEMBL9103893

CCCS(=O)(=O)ON1c2ccccc2Oc2c(Br)cccc21

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
P2RX4 Q99571 5/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
P2RX1 P51575 1/20 0.33
RXFP1 Q9HBX9 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9102641 0.89 P2RX4 (0.36) P2RX4MEN1KMT2AP2RX1RXFP1
SCHEMBL9100971 0.86 P2RX4 (0.35) P2RX4P2RX1
SCHEMBL9103561 0.86 KDM4E (0.34) P2RX4P2RX1
SCHEMBL9104785 0.85 AHR (0.38) P2RX4MEN1KMT2AP2RX1
SCHEMBL9101955 0.84 KDM4E (0.33) P2RX4P2RX1
SCHEMBL9104487 0.84 P2RX4 (0.41) P2RX4MEN1KMT2AP2RX1
SCHEMBL9104489 0.84 P2RX4 (0.43) P2RX4P2RX1
SCHEMBL9105178 0.82 NR1H2 (0.33) P2RX4MEN1KMT2AP2RX1
SCHEMBL9099192 0.81 AHR (0.39) P2RX4MEN1KMT2AP2RX1RXFP1
SCHEMBL9101909 0.81 AHR (0.39) P2RX4MEN1KMT2AP2RX1RXFP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8192948-B1 Chemifluorescent substrate for peroxide and peroxidase detection PIERCE BIOTECHNOLOGY, INC. (US) 2012-06-05 US disclosed
EP-0361470-B1 Method for the chemiluminescence assay of the activity of peroxidase FUJIREBIO KK (JP) 1993-12-22 EP disclosed
US-5171668-A Measuring light emitted from contacting (iso)luminol, peroxide, peroxidase activity enhancer, such as indoanilines, phenolindophenol and N-methylphenothiazine, with labeled peroxidase antibody-antigen complex FUJIREBIO INC. (JP) 1992-12-15 US disclosed
EP-0361470-A2 Method for the chemiluminescence assay of the activity of peroxidase FUJIREBIO INC. (JP) 1990-04-04 EP disclosed