Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 3/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5053864 | 0.92 | ABCB1 (0.61) | ABCB1CYP3A4CYP2C9 | |
| SCHEMBL583844 | 0.89 | ABCB1 (0.67) | ABCB1CYP3A4 | |
| SCHEMBL8387173 | 0.86 | ABCB1 (0.62) | ABCB1 | |
| SCHEMBL5062581 | 0.84 | ABCB1 (0.57) | ABCB1CYP3A4CYP2C9 | |
| SCHEMBL17604610 | 0.83 | ABCB1 (0.48) | ABCB1 | |
| SCHEMBL5062538 | 0.83 | ABCB1 (0.55) | ABCB1 | |
| SCHEMBL5057173 | 0.83 | ABCB1 (0.61) | ABCB1CYP3A4CYP2C9 | |
| SCHEMBL9102034 | 0.82 | ABCB1 (0.54) | ABCB1 | |
| SCHEMBL18091869 | 0.81 | ABCB1 (0.55) | ABCB1 | |
| SCHEMBL64477 | 0.81 | ABCB1 (0.77) | ABCB1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2460786-B1 | Bioavailable diacylhydrazine ligands for modulating the expression of exogenous genes via an ecdysone receptor complex | INTREXON CORP (US) | 2016-01-13 | — | — | EP | disclosed |
| EP-2460786-A1 | Bioavailable diacylhydrazine ligands for modulating the expression of exogenous genes via an ecdysone receptor complex | Intrexon Corporation (US) | 2012-06-06 | — | — | EP | disclosed |