Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | CA12 | O43570 | 5/20 | 0.41 |
| ▸ | CA1 | P00915 | 5/20 | 0.41 |
| ▸ | CA2 | P00918 | 5/20 | 0.41 |
| ▸ | CA9 | Q16790 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | THRB | P10828 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | CA4 | P22748 | 3/20 | 0.40 |
| ▸ | CA6 | P23280 | 3/20 | 0.40 |
| ▸ | CA5A | P35218 | 3/20 | 0.40 |
| ▸ | CA7 | P43166 | 3/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL9103041 | 0.90 | ALDH1A1 (0.48) | ALDH1A1HSD17B10CA12CA1CA2 | |
| SCHEMBL1456970 | 0.83 | CYP3A4 (0.55) | ALDH1A1HSD17B10CA12CA1CA2 | |
| Hydrochloric Acid SCHEMBL8045536 | 0.81 | CYP3A4 (0.52) | ALDH1A1HSD17B10CA12CA1CA2 | |
| Hydrochloric Acid SCHEMBL29972242 | 0.81 | CYP3A4 (0.52) | ALDH1A1HSD17B10CA12CA1CA2 | |
| SCHEMBL30523470 | 0.69 | AURKA (0.44) | ALDH1A1HSD17B10CA12CA1CA2 | |
| SCHEMBL11362089 | 0.69 | AURKA (0.44) | ALDH1A1HSD17B10CA12CA1CA2 | |
| SCHEMBL7605518 | 0.69 | CA1 (0.73) | ALDH1A1HSD17B10CA12CA1CA2 | |
| SCHEMBL526351 | 0.68 | ALDH1A1 (0.50) | ALDH1A1HSD17B10CA12CA1CA2 | |
| SCHEMBL31392414 | 0.68 | CYP3A4 (0.75) | ALDH1A1HSD17B10CA12CA1CA2 | |
| SCHEMBL68064 | 0.68 | CYP3A4 (0.75) | ALDH1A1HSD17B10CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5545754-A | Process for the preparation of p-amino-phenols | BAYER AKTIENGESELLSCHAFT (DE) | 1996-08-13 | — | — | US | disclosed |