Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL155434 | 0.81 | TSHR (0.68) | TP53TSHRALDH1A1HSD17B10TDP1 | |
| SCHEMBL29631091 | 0.81 | TSHR (0.68) | TP53TSHRALDH1A1HSD17B10TDP1 | |
| Benzene SCHEMBL12472151 | 0.79 | TSHR (0.71) | TP53TSHRALDH1A1HSD17B10TDP1 | |
| SCHEMBL11655234 | 0.79 | TSHR (0.66) | TP53TSHRALDH1A1HSD17B10TDP1 | |
| SCHEMBL4089780 | 0.79 | TP53 (0.67) | TP53TSHRALDH1A1HCRTR1HCRTR2 | |
| SCHEMBL8932267 | 0.79 | ALDH1A1 (0.54) | TP53TSHRALDH1A1HSD17B10TDP1 | |
| SCHEMBL2477857 | 0.75 | ALDH1A1 (0.65) | TSHRALDH1A1HSD17B10TDP1KDM4E | |
| SCHEMBL2439254 | 0.75 | TSHR (0.59) | TP53TSHRALDH1A1HSD17B10TDP1 | |
| SCHEMBL155433 | 0.75 | TSHR (0.59) | TP53TSHRALDH1A1HSD17B10TDP1 | |
| SCHEMBL9108602 | 0.74 | ALDH1A1 (0.47) | TSHRALDH1A1HSD17B10TDP1HCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5451654-A | Addition polymerization catalyst | ELF ATOCHEM NORTH AMERICA, INC. (US) | 1995-09-19 | — | — | US | disclosed |
| US-5387654-A | Hydroxy-peroxides and their uses | ELF ATOCHEM NORTH AMERICA, INC. (US) | 1995-02-07 | — | — | US | disclosed |
| EP-0381135-B1 | Novel hydroxy-peroxides and their uses | ATOCHEM NORTH AMERICA (US) | 1994-06-01 | — | — | EP | disclosed |
| US-5304649-A | Curing agent for unsaturated polyesters | ELF ATOCHEM NORTH AMERICA, INC. (US) | 1994-04-19 | — | — | US | disclosed |
| EP-0381135-A2 | Novel hydroxy-peroxides and their uses | ATOCHEM NORTH AMERICA, INC. (US) | 1990-08-08 | — | — | EP | disclosed |