⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9104011 | 0.93 | HDAC3 (0.31) | — | |
| SCHEMBL9105026 | 0.88 | P2RX4 (0.32) | — | |
| SCHEMBL9101857 | 0.86 | APLNR (0.32) | — | |
| SCHEMBL9100387 | 0.86 | KCNH2 (0.32) | — | |
| SCHEMBL9100410 | 0.85 | BCHE (0.32) | — | |
| SCHEMBL9104492 | 0.83 | P2RX4 (0.37) | — | |
| SCHEMBL9106479 | 0.81 | TP53 (0.32) | — | |
| SCHEMBL9100194 | 0.81 | P2RX4 (0.32) | — | |
| SCHEMBL18048012 | 0.78 | P2RX4 (0.30) | — | |
| SCHEMBL9105156 | 0.78 | P2RX4 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8192948-B1 | Chemifluorescent substrate for peroxide and peroxidase detection | PIERCE BIOTECHNOLOGY, INC. (US) | 2012-06-05 | — | — | US | disclosed |
| EP-0361470-B1 | Method for the chemiluminescence assay of the activity of peroxidase | FUJIREBIO KK (JP) | 1993-12-22 | — | — | EP | disclosed |
| US-5171668-A | Measuring light emitted from contacting (iso)luminol, peroxide, peroxidase activity enhancer, such as indoanilines, phenolindophenol and N-methylphenothiazine, with labeled peroxidase antibody-antigen complex | FUJIREBIO INC. (JP) | 1992-12-15 | — | — | US | disclosed |
| EP-0361470-A2 | Method for the chemiluminescence assay of the activity of peroxidase | FUJIREBIO INC. (JP) | 1990-04-04 | — | — | EP | disclosed |