⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1192596 | 0.88 | — | — | |
| SCHEMBL1193326 | 0.88 | — | — | |
| SCHEMBL969704 | 0.86 | SHBG (0.56) | — | |
| SCHEMBL892135 | 0.86 | SHBG (0.56) | — | |
| SCHEMBL1193182 | 0.86 | SHBG (0.56) | — | |
| SCHEMBL7994471 | 0.82 | SHBG (0.31) | — | |
| SCHEMBL7003852 | 0.77 | — | — | |
| SCHEMBL4455263 | 0.77 | SHBG (0.30) | — | |
| SCHEMBL7998104 | 0.75 | SHBG (0.35) | — | |
| SCHEMBL7998100 | 0.75 | SHBG (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 277 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004035636-A2 | POLYMERIZED CYCLOOLEFINS USING TRANSITION METAL CATALYST AND END PRODUCTS THEREOF | PROMERUS, LLC (US) | 2004-04-29 | — | — | WO | claimed |
| US-20240208928-A1 | NOVEL COMPOUNDS | HOFFMANN-LA ROCHE INC. (US) | 2024-06-27 | — | — | US | disclosed |
| WO-2024099993-A1 | TRIAZINONE DERIVATIVES AS NLRP3 INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2024-05-16 | — | — | WO | disclosed |
| US-20240132471-A1 | NOVEL COMPOUNDS | HOFFMANN-LA ROCHE INC. (US) | 2024-04-25 | — | — | US | disclosed |
| EP-4347571-A1 | TRIAZINE DERIVATIVES AND THEIR USE IN THE TREATMENT OF CANCER | F. Hoffmann-La Roche AG (CH) | 2024-04-10 | — | — | EP | disclosed |
| CN-117794910-A | NLRP3 inhibitors | 豪夫迈·罗氏有限公司 | 2024-03-29 | — | — | CN | disclosed |
| CN-114746405-B | Novel BRAF inhibitors as anomalous breakers | 豪夫迈·罗氏有限公司 | 2024-03-26 | — | — | CN | disclosed |
| EP-4337652-A1 | NLRP3 INHIBITORS | F. Hoffmann-La Roche AG (CH) | 2024-03-20 | — | — | EP | disclosed |
| CN-117460718-A | Triazine derivatives and their use in the treatment of cancer | 豪夫迈·罗氏有限公司 | 2024-01-26 | — | — | CN | disclosed |
| CN-117285525-A | Novel isoxazolyl ether derivatives as GABAA alpha 5PAM | 豪夫迈·罗氏有限公司 | 2023-12-26 | — | — | CN | disclosed |
| WO-1998038169-A1 | SUBSTITUTED 3-PHENYL PYRAZOLES | BASF AKTIENGESELLSCHAFT (DE) | 1998-09-03 | — | — | WO | disclosed |
| WO-1998012182-A1 | 1-SULFONYL-3-PHENYLPYRAZOLES AND THEIR USE AS HERBICIDES AND FOR DESICCATING OR DEFOLIATING PLANTS | BASF AKTIENGESELLSCHAFT (DE) | 1998-03-26 | — | — | WO | disclosed |
| WO-1998007720-A1 | SUBSTITUTED 2-ARYLPYRIDINE AS HERBICIDE | BASF AKTIENGESELLSCHAFT (DE) | 1998-02-26 | — | — | WO | disclosed |
| WO-1998005649-A1 | SUBSTITUTED 3-PHENYL PYRAZOLES | BASF AKTIENGESELLSCHAFT (DE) | 1998-02-12 | — | — | WO | disclosed |
| US-5712267-A | Carbapenem derivatives, their preparation and their use as antibiotics | SANKYO COMPANY,. LIMITED (JP) | 1998-01-27 | — | — | US | disclosed |
| WO-1997015559-A1 | SUBSTITUTED 4,5-DI(TRIFLUOROMETHYL)PYRAZOLES AND THEIR USE AS HERBICIDES AND FOR DESICCATING/DEFOLIATING PLANTS | BASF AKTIENGESELLSCHAFT (DE) | 1997-05-01 | — | — | WO | disclosed |
| EP-0560613-A1 | Antimicrobial carbapenem derivatives, their preparation and their therapeutic use | SANKYO COMPANY LIMITED (JP) | 1993-09-15 | — | — | EP | disclosed |
| EP-0177287-B1 | PYRIMIDINE DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND COMPOSITION OF THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-12-05 | — | — | EP | disclosed |
| US-4727073-A | CEREBOVASCULAR DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-02-23 | — | — | US | disclosed |
| EP-0177287-A2 | Pyrimidine derivatives, processes for preparation thereof and composition of the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-04-09 | — | — | EP | disclosed |