SCHEMBL9104016

SCHEMBL9104016

CCc1cccc2c1Sc1cccc(CC)c1N2C(CC)S(=O)(=O)O

nearest known ligand 0.36

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
RAD52 P43351 1/20 0.36
GABRA1 P14867 1/20 0.32
GABRB2 P47870 1/20 0.32
BCHE P06276 2/20 0.32
MAPT P10636 1/20 0.32
CRHBP P24387 1/20 0.31
CRHR2 Q13324 1/20 0.31
ANPEP P15144 2/20 0.30
DPP4 P27487 2/20 0.30
NOX1 Q9Y5S8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9104783 0.90 RAD52 (0.31) RAD52BCHEMAPT
SCHEMBL9103393 0.89 RAD52 (0.39) RAD52GABRA1GABRB2BCHEMAPT
SCHEMBL9100651 0.89 BCHE (0.40) BCHEMAPTNOX1
SCHEMBL9105582 0.88 RAD52 (0.32) RAD52ANPEPDPP4
SCHEMBL9102671 0.88 RAD52 (0.32) RAD52
SCHEMBL9102133 0.88 BCHE (0.31) RAD52BCHE
SCHEMBL9102550 0.83 BCHE (0.32) BCHEMAPTNOX1
SCHEMBL9102580 0.81 CYP2D6 (0.39) BCHEMAPTANPEPDPP4NOX1
SCHEMBL9102163 0.81 RAD52 (0.32) RAD52MAPT
SCHEMBL9104568 0.81 BCHE (0.35) RAD52BCHEMAPTNOX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8192948-B1 Chemifluorescent substrate for peroxide and peroxidase detection PIERCE BIOTECHNOLOGY, INC. (US) 2012-06-05 US disclosed
EP-0361470-B1 Method for the chemiluminescence assay of the activity of peroxidase FUJIREBIO KK (JP) 1993-12-22 EP disclosed
US-5171668-A Measuring light emitted from contacting (iso)luminol, peroxide, peroxidase activity enhancer, such as indoanilines, phenolindophenol and N-methylphenothiazine, with labeled peroxidase antibody-antigen complex FUJIREBIO INC. (JP) 1992-12-15 US disclosed
EP-0361470-A2 Method for the chemiluminescence assay of the activity of peroxidase FUJIREBIO INC. (JP) 1990-04-04 EP disclosed