SCHEMBL9102550

SCHEMBL9102550

CCC(N1c2cccc(C)c2Sc2cccc(C)c21)S(=O)(=O)O

nearest known ligand 0.32

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
BCHE P06276 5/20 0.32
TSHR P16473 2/20 0.32
CYP2D6 P10635 1/20 0.32
CYP2C19 P33261 1/20 0.32
ACHE P22303 1/20 0.32
MAPT P10636 1/20 0.32
MAPK1 P28482 1/20 0.31
LMNA P02545 1/20 0.30
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30
NOX1 Q9Y5S8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9105514 0.89 BCHE (0.41) BCHETSHRCYP2D6CYP2C19ACHE
SCHEMBL9100969 0.89 BCHE (0.38) BCHETSHRCYP2D6CYP2C19ACHE
SCHEMBL9100996 0.89 NR3C1 (0.33)
SCHEMBL9099981 0.89 NR3C1 (0.33)
SCHEMBL9104016 0.83 RAD52 (0.36) BCHEMAPTNOX1
SCHEMBL9105222 0.82 DRD3 (0.31) BCHEMAPTMEN1KMT2A
SCHEMBL9105616 0.82 BCHE (0.35) BCHETSHRCYP2D6CYP2C19ACHE
SCHEMBL9104783 0.80 RAD52 (0.31) BCHETSHRCYP2D6CYP2C19ACHE
SCHEMBL9102133 0.78 BCHE (0.31) BCHE
SCHEMBL9100651 0.77 BCHE (0.40) BCHETSHRCYP2D6CYP2C19ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8192948-B1 Chemifluorescent substrate for peroxide and peroxidase detection PIERCE BIOTECHNOLOGY, INC. (US) 2012-06-05 US disclosed
EP-0361470-B1 Method for the chemiluminescence assay of the activity of peroxidase FUJIREBIO KK (JP) 1993-12-22 EP disclosed
US-5171668-A Measuring light emitted from contacting (iso)luminol, peroxide, peroxidase activity enhancer, such as indoanilines, phenolindophenol and N-methylphenothiazine, with labeled peroxidase antibody-antigen complex FUJIREBIO INC. (JP) 1992-12-15 US disclosed
EP-0361470-A2 Method for the chemiluminescence assay of the activity of peroxidase FUJIREBIO INC. (JP) 1990-04-04 EP disclosed