Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.49 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | GFER | P55789 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.43 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16173977 | 0.84 | TSHR (0.50) | DRD4KMT2AMEN1SMN1; SMN2GAA | |
| SCHEMBL10133724 | 0.83 | KMT2A (0.49) | DRD4KMT2AMEN1SMN1; SMN2GAA | |
| SCHEMBL11317311 | 0.78 | TSHR (0.52) | DRD4KMT2AMEN1SMN1; SMN2GAA | |
| Diethylaniline SCHEMBL28106634 | 0.77 | ALDH1A1 (0.57) | KMT2AMEN1SMN1; SMN2GAAMAPT | |
| SCHEMBL11659110 | 0.77 | TAAR1 (0.40) | DRD4KMT2AMEN1SMN1; SMN2MAPT | |
| SCHEMBL17346231 | 0.77 | DRD4 (0.45) | DRD4KMT2AMEN1SMN1; SMN2GAA | |
| SCHEMBL10678638 | 0.77 | TSHR (0.64) | KMT2AMEN1SMN1; SMN2GAAMAPT | |
| SCHEMBL8394269 | 0.76 | GAA (0.53) | KMT2AMEN1SMN1; SMN2GAAMAPT | |
| SCHEMBL9180518 | 0.76 | KMT2A (0.72) | KMT2AMEN1SMN1; SMN2GAAMAPT | |
| SCHEMBL8380659 | 0.76 | TSHR (0.53) | KMT2AMEN1GAAMAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0474431-B1 | Amphiphilic compounds for sequential monolayer deposition | ICI PLC (GB) | 1996-03-06 | — | — | EP | disclosed |
| US-5275924-A | Non-centrosymmetric; hydrophobic; chromophores | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1994-01-04 | — | — | US | disclosed |
| EP-0474431-A1 | Amphiphilic compounds for sequential monolayer deposition | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-03-11 | — | — | EP | disclosed |