SCHEMBL9104250

SCHEMBL9104250

CCCS(=O)(=O)ON1c2ccccc2Sc2c(Br)cccc21

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCHE P06276 11/20 0.35
MAPT P10636 3/20 0.33
HTT P42858 2/20 0.33
NPSR1 Q6W5P4 1/20 0.33
SLC6A3 Q01959 1/20 0.32
PDF Q9HBH1 3/20 0.32
POLB P06746 3/20 0.32
GAA P10253 1/20 0.32
ATM Q13315 1/20 0.32
KDM1A O60341 1/20 0.30
MAOA P21397 1/20 0.30
KDM4E B2RXH2 1/20 0.30
MEN1 O00255 1/20 0.30
ALDH1A1 P00352 1/20 0.30
TP53 P04637 1/20 0.30
ALOX15 P16050 1/20 0.30
ALOX12 P18054 1/20 0.30
CASP1 P29466 1/20 0.30
RAB9A P51151 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9102832 0.88 BCHE (0.37) BCHEMAPTHTTNPSR1SLC6A3
SCHEMBL9103401 0.86 BCHE (0.35) BCHEMAPTHTTNPSR1POLB
SCHEMBL9100982 0.86 BCHE (0.38) BCHEMAPTHTTNPSR1POLB
SCHEMBL9105699 0.86 BCHE (0.38) BCHEMAPTHTTNPSR1POLB
SCHEMBL9547663 0.86 BCHE (0.45) BCHEMAPTHTTNPSR1POLB
SCHEMBL9104584 0.84 BCHE (0.34) BCHEMAPTHTTNPSR1POLB
SCHEMBL7519303 0.84 BCHE (0.44) BCHEMAPTHTTNPSR1POLB
SCHEMBL7519307 0.84 BCHE (0.44) BCHEMAPTHTTNPSR1POLB
SCHEMBL9106151 0.82 BCHE (0.37) BCHEMAPTHTTNPSR1SLC6A3
SCHEMBL9100940 0.81 BCHE (0.40) BCHEMAPTHTTNPSR1SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8192948-B1 Chemifluorescent substrate for peroxide and peroxidase detection PIERCE BIOTECHNOLOGY, INC. (US) 2012-06-05 US disclosed
EP-0361470-B1 Method for the chemiluminescence assay of the activity of peroxidase FUJIREBIO KK (JP) 1993-12-22 EP disclosed
US-5171668-A Measuring light emitted from contacting (iso)luminol, peroxide, peroxidase activity enhancer, such as indoanilines, phenolindophenol and N-methylphenothiazine, with labeled peroxidase antibody-antigen complex FUJIREBIO INC. (JP) 1992-12-15 US disclosed
EP-0361470-A2 Method for the chemiluminescence assay of the activity of peroxidase FUJIREBIO INC. (JP) 1990-04-04 EP disclosed