SCHEMBL9105699

SCHEMBL9105699

CCCS(=O)(=O)ON1c2ccccc2Sc2c(Cl)cccc21

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCHE P06276 9/20 0.38
PLK4 O00444 1/20 0.34
AURKA O14965 1/20 0.34
MAPK13 O15264 1/20 0.34
ROCK2 O75116 1/20 0.34
RPS6KA5 O75582 1/20 0.34
PRKD3 O94806 1/20 0.34
MAP4K4 O95819 1/20 0.34
CDK1 P06493 1/20 0.34
IGF1R P08069 1/20 0.34
ROS1 P08922 1/20 0.34
PIM1 P11309 1/20 0.34
PHKG2 P15735 1/20 0.34
FER P16591 1/20 0.34
PRKACA P17612 1/20 0.34
RPS6KB1 P23443 1/20 0.34
CDK2 P24941 1/20 0.34
MARK3 P27448 1/20 0.34
AXL P30530 1/20 0.34
FLT4 P35916 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9100982 0.88 BCHE (0.38) BCHEMAPTNPSR1HPGDALOX12
SCHEMBL9103401 0.88 BCHE (0.35) BCHEMAPTNPSR1HTTPOLB
SCHEMBL9547663 0.87 BCHE (0.45) BCHEMAPTNPSR1HTTPOLB
SCHEMBL9104250 0.86 BCHE (0.35) BCHEMAPTNPSR1ALDH1A1ALOX12
SCHEMBL9100592 0.86 HDAC1 (0.40) BCHEMAPTNPSR1HTTPOLB
SCHEMBL9104584 0.85 BCHE (0.34) BCHEMAPTNPSR1MYLKHTT
SCHEMBL7519307 0.85 BCHE (0.44) BCHEMAPTNPSR1HTTPOLB
SCHEMBL7519303 0.85 BCHE (0.44) BCHEMAPTNPSR1HTTPOLB
SCHEMBL9106151 0.83 BCHE (0.37) BCHEMAPTNPSR1MYLKHPGD
SCHEMBL9102312 0.81 SNCA (0.45) BCHEMAPTMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8192948-B1 Chemifluorescent substrate for peroxide and peroxidase detection PIERCE BIOTECHNOLOGY, INC. (US) 2012-06-05 US disclosed
EP-0361470-B1 Method for the chemiluminescence assay of the activity of peroxidase FUJIREBIO KK (JP) 1993-12-22 EP disclosed
US-5171668-A Measuring light emitted from contacting (iso)luminol, peroxide, peroxidase activity enhancer, such as indoanilines, phenolindophenol and N-methylphenothiazine, with labeled peroxidase antibody-antigen complex FUJIREBIO INC. (JP) 1992-12-15 US disclosed
EP-0361470-A2 Method for the chemiluminescence assay of the activity of peroxidase FUJIREBIO INC. (JP) 1990-04-04 EP disclosed