SCHEMBL9104314

SCHEMBL9104314

CC(O)COOC(=O)c1ccccc1C(=O)O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.49
TSHR P16473 2/20 0.49
ALOX15 P16050 1/20 0.45
LMNA P02545 1/20 0.43
USP2 O75604 1/20 0.41
TP53 P04637 1/20 0.41
CYP1A2 P05177 1/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
KDM4E B2RXH2 3/20 0.39
HPGD P15428 1/20 0.39
HSD17B10 Q99714 1/20 0.39
MAPT P10636 1/20 0.39
HDAC8 Q9BY41 1/20 0.39
TAAR1 Q96RJ0 1/20 0.39
AKR1C3 P42330 1/20 0.38
MEN1 O00255 1/20 0.38
RECQL P46063 1/20 0.38
KMT2A Q03164 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30306347 0.83 ALDH1A1 (0.66) ALDH1A1TSHRALOX15LMNATP53
SCHEMBL4597929 0.83 ALDH1A1 (0.66) ALDH1A1TSHRALOX15LMNATP53
SCHEMBL9106298 0.83 ALDH1A1 (0.45) ALDH1A1TSHRALOX15LMNACYP1A2
SCHEMBL1300443 0.81 ALDH1A1 (0.67) ALDH1A1TSHRLMNATP53CYP3A4
SCHEMBL840674 0.80 ALDH1A1 (0.61) ALDH1A1TSHRALOX15TP53CYP3A4
Trimethylammonium SCHEMBL28124203 0.79 ALDH1A1 (0.60) ALDH1A1TSHRALOX15LMNACYP3A4
SCHEMBL21378338 0.78 ALDH1A1 (0.45) ALDH1A1TSHRALOX15CYP3A4KDM4E
Phthalic Acid SCHEMBL840675 0.77 ALDH1A1 (0.45) ALDH1A1TSHRALOX15LMNAUSP2
Fumaric Acid SCHEMBL11600043 0.77 ALDH1A1 (0.57) ALDH1A1TSHRALOX15LMNACYP3A4
SCHEMBL31590867 0.77 TSHR (0.52) ALDH1A1TSHRALOX15LMNATP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5451654-A Addition polymerization catalyst ELF ATOCHEM NORTH AMERICA, INC. (US) 1995-09-19 US disclosed
US-5387654-A Hydroxy-peroxides and their uses ELF ATOCHEM NORTH AMERICA, INC. (US) 1995-02-07 US disclosed
EP-0381135-B1 Novel hydroxy-peroxides and their uses ATOCHEM NORTH AMERICA (US) 1994-06-01 EP disclosed
US-5304649-A Curing agent for unsaturated polyesters ELF ATOCHEM NORTH AMERICA, INC. (US) 1994-04-19 US disclosed
EP-0381135-A2 Novel hydroxy-peroxides and their uses ATOCHEM NORTH AMERICA, INC. (US) 1990-08-08 EP disclosed