Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 1/20 | 0.51 |
| ▸ | NQO1 | P15559 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | PGK1 | P00558 | 1/20 | 0.46 |
| ▸ | PGK2 | P07205 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.46 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3723566 | 0.83 | NCF1 (0.47) | NCF1NQO1HDAC1HDAC2KDM4E | |
| SCHEMBL31018934 | 0.83 | NCF1 (0.47) | NCF1NQO1HDAC1HDAC2KDM4E | |
| SCHEMBL22353374 | 0.82 | KDM4E (0.43) | NCF1NQO1HDAC1HDAC2KDM4E | |
| SCHEMBL7808259 | 0.81 | NCF1 (0.57) | NCF1NQO1HDAC1HDAC2KDM4E | |
| SCHEMBL7835368 | 0.79 | NCF1 (0.59) | NCF1NQO1HDAC1HDAC2KDM4E | |
| SCHEMBL31434375 | 0.78 | NCF1 (0.54) | NCF1NQO1HDAC1HDAC2KDM4E | |
| SCHEMBL4849365 | 0.78 | NCF1 (0.57) | NCF1NQO1HDAC1HDAC2KDM4E | |
| Ammonia Solution, Strong SCHEMBL28426316 | 0.78 | NCF1 (0.57) | NCF1NQO1HDAC1HDAC2KDM4E | |
| SCHEMBL203756 | 0.78 | NCF1 (0.57) | NCF1NQO1HDAC1HDAC2KDM4E | |
| SCHEMBL28254830 | 0.78 | NCF1 (0.62) | NCF1NQO1HDAC1HDAC2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210255203-A1 | NOVEL COMPOUNDS USEFUL AS NEAR-INFRARED FLUORESCENT PROBES SELECTIVELY BINDING TO TAU AGGREGATES AND METHOD OF PREPARING THE SAME | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2021-08-19 | — | — | US | disclosed |
| US-20120142690-A1 | Substituted piperidines | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210255203-A1 | NOVEL COMPOUNDS USEFUL AS NEAR-INFRARED FLUORESCENT PROBES SELECTIVELY BINDING TO TAU AGGREGATES AND METHOD OF PREPARING THE SAME | MAPT, PSEN1, PSEN2 | NCF1 1690/4885NQO1 2775/4885HDAC1 2471/4885 |
| US-20120142690-A1 | Substituted piperidines | VHL, PIR, PIGO | NCF1 2107/4885NQO1 117/4885HDAC1 2109/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.