Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATP4A | P20648 | 7/20 | 0.52 |
| ▸ | ATP4B | P51164 | 7/20 | 0.52 |
| ▸ | NPC1 | O15118 | 5/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.47 |
| ▸ | RELA | Q04206 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4656737 | 0.91 | ATP4A (0.50) | ATP4AATP4BNPC1NFKB1NFKB2 | |
| SCHEMBL4655616 | 0.91 | ATP4A (0.53) | ATP4AATP4BNPC1NFKB1NFKB2 | |
| SCHEMBL4656445 | 0.90 | ATP4A (0.49) | ATP4AATP4BNPC1NFKB1NFKB2 | |
| SCHEMBL4656417 | 0.90 | ATP4A (0.52) | ATP4AATP4BNPC1NFKB1NFKB2 | |
| SCHEMBL4656576 | 0.90 | ATP4A (0.52) | ATP4AATP4BNPC1NFKB1NFKB2 | |
| SCHEMBL5429220 | 0.88 | ATP4A (0.50) | ATP4AATP4BNPC1NFKB1NFKB2 | |
| SCHEMBL4656438 | 0.86 | ATP4A (0.49) | ATP4AATP4BNPC1NFKB1NFKB2 | |
| SCHEMBL5419935 | 0.86 | ATP4A (0.49) | ATP4AATP4BNPC1NFKB1NFKB2 | |
| SCHEMBL5417643 | 0.83 | ATP4A (0.46) | ATP4AATP4BNPC1NFKB1NFKB2 | |
| SCHEMBL3128282 | 0.81 | ATP4A (0.52) | ATP4AATP4BNPC1NFKB1NFKB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2460800-A1 | Substituted aminothiazole derivatives with anti-HCV activity | Achillion Pharmaceuticals, Inc. (US) | 2012-06-06 | — | — | EP | disclosed |