SCHEMBL9105527

SCHEMBL9105527

CCCS(=O)(=O)ON1c2ccccc2Sc2cccc(C)c21

nearest known ligand 0.41

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
BCHE P06276 13/20 0.41
MAPT P10636 3/20 0.36
POLB P06746 2/20 0.36
NOX1 Q9Y5S8 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
HTT P42858 1/20 0.36
CYP2D6 P10635 1/20 0.35
TSHR P16473 1/20 0.35
CYP2C19 P33261 1/20 0.35
GAA P10253 1/20 0.35
ATM Q13315 1/20 0.35
ACHE P22303 1/20 0.34
MAOA P21397 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9102563 0.89 BCHE (0.32) BCHETSHR
SCHEMBL9105629 0.88 BCHE (0.36) BCHEMAPTPOLBHTT
SCHEMBL9100671 0.88 BCHE (0.38) BCHEMAPTPOLBNOX1NPSR1
SCHEMBL9104975 0.87 BCHE (0.39) BCHEMAPTNOX1NPSR1HTT
SCHEMBL9547663 0.87 BCHE (0.45) BCHEMAPTPOLBNOX1NPSR1
SCHEMBL9100592 0.86 HDAC1 (0.40) BCHEMAPTPOLBNOX1NPSR1
SCHEMBL9102832 0.86 BCHE (0.37) BCHEMAPTPOLBNOX1NPSR1
SCHEMBL9105213 0.85 BCHE (0.36) BCHEMAPTPOLBNOX1NPSR1
SCHEMBL7519303 0.85 BCHE (0.44) BCHEMAPTPOLBNOX1NPSR1
SCHEMBL7519307 0.85 BCHE (0.44) BCHEMAPTPOLBNOX1NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8192948-B1 Chemifluorescent substrate for peroxide and peroxidase detection PIERCE BIOTECHNOLOGY, INC. (US) 2012-06-05 US disclosed
EP-0361470-B1 Method for the chemiluminescence assay of the activity of peroxidase FUJIREBIO KK (JP) 1993-12-22 EP disclosed
US-5171668-A Measuring light emitted from contacting (iso)luminol, peroxide, peroxidase activity enhancer, such as indoanilines, phenolindophenol and N-methylphenothiazine, with labeled peroxidase antibody-antigen complex FUJIREBIO INC. (JP) 1992-12-15 US disclosed
EP-0361470-A2 Method for the chemiluminescence assay of the activity of peroxidase FUJIREBIO INC. (JP) 1990-04-04 EP disclosed