SCHEMBL9105629

SCHEMBL9105629

CCCS(=O)(=O)ON1c2cc(C)ccc2Sc2cccc(C)c21

nearest known ligand 0.36

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
BCHE P06276 6/20 0.36
MAPT P10636 4/20 0.33
TP53 P04637 2/20 0.33
POLB P06746 1/20 0.33
LMNA P02545 1/20 0.32
ALDH1A1 P00352 3/20 0.32
SMN1; SMN2 Q16637 1/20 0.30
KMT2A Q03164 3/20 0.30
MEN1 O00255 2/20 0.30
HPGD P15428 1/20 0.30
ALOX12 P18054 1/20 0.30
KDM4E B2RXH2 1/20 0.30
F2 P00734 1/20 0.30
XBP1 P17861 1/20 0.30
HTT P42858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9105527 0.88 BCHE (0.41) BCHEMAPTPOLBHTT
SCHEMBL9107471 0.87 KDM4E (0.30) MAPTALDH1A1KDM4EF2
SCHEMBL9104158 0.86 BCHE (0.41) BCHEMAPTLMNAALDH1A1KMT2A
SCHEMBL9101005 0.85 NR3C1 (0.31)
SCHEMBL9102563 0.82 BCHE (0.32) BCHEKMT2AMEN1
SCHEMBL9104058 0.82 BCHE (0.32) BCHEPOLBKMT2A
SCHEMBL9104975 0.81 BCHE (0.39) BCHEMAPTHTT
SCHEMBL9102428 0.79 BCHE (0.41) BCHEMAPTLMNAALDH1A1KMT2A
SCHEMBL9102590 0.79 CYP2D6 (0.36) MAPTTP53LMNAALDH1A1SMN1; SMN2
SCHEMBL9104611 0.78 P2RX4 (0.35) MAPTLMNAALDH1A1SMN1; SMN2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8192948-B1 Chemifluorescent substrate for peroxide and peroxidase detection PIERCE BIOTECHNOLOGY, INC. (US) 2012-06-05 US disclosed
EP-0361470-B1 Method for the chemiluminescence assay of the activity of peroxidase FUJIREBIO KK (JP) 1993-12-22 EP disclosed
US-5171668-A Measuring light emitted from contacting (iso)luminol, peroxide, peroxidase activity enhancer, such as indoanilines, phenolindophenol and N-methylphenothiazine, with labeled peroxidase antibody-antigen complex FUJIREBIO INC. (JP) 1992-12-15 US disclosed
EP-0361470-A2 Method for the chemiluminescence assay of the activity of peroxidase FUJIREBIO INC. (JP) 1990-04-04 EP disclosed